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Example sentences for: akxd-

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Additional studies may also identify " normal" mouse strains that develop increased IOP with age as generally occurs in Western populations [ 52 53 ] . We previously demonstrated that the glaucomatous strains DBA/2J and AKXD-28/Ty develop elevated IOP with age [ 14 19 ] .
Additionally, AKXD-28/Ty mice contain D2 derived microsatellite markers for D6Mit207 , D6Mit33 , and D6Mit93 which subdivide this region and are tightly linked to ipd (data not shown).
The mouse strains used in this study were DBA/2J (D2), AKXD-28/Ty (AKXD28), and C57BL/6J (B6).
This is in agreement with a number of human studies, which show that IOP is equal between the sexes [ 52 53 ] . However, some studies have found sex-specific differences (typically with higher IOP in females and the magnitude of the difference increasing after 40 years of age) [ 53 54 ] . Of possible relevance, we previously reported that female mice of strains DBA/2J and AKXD-28/Ty develop elevated IOP at an earlier age than males [ 14 19 ] .
Here we report differences in genetic susceptibility to glaucoma-associated phenotypes between two related inbred strains of mice, AKXD-28/Ty (AKXD28) and DBA/2J (D2).