Words similar to akt
Example sentences for: akt
How can you use “akt” in a sentence? Here are some example sentences to help you improve your vocabulary:
This result may seem paradoxical since increased phosphorylated AKT, due to inactivation of Pten , suppresses apoptosis and promotes proliferation.
Although it is often assumed that elevated Akt activity is responsible for the increased survival of cancer cells, Akt activity is not the only pathway that is essential for cell survival.
As expected, phosphorylated AKT was undetectable in hyperplastic ducts, in tumors from Wnt-1 TG, Pten +/+ mice, and tumors from Wnt-1 TG, Pten +/- mice that retained the wild type allele (Fig.
Inactivation of Pten promotes membrane recruitment of AKT and its subsequent activation by phosphorylation at Ser473 and Thr308 [ 10, 11, 13].
One such candidate is the rapamycin analog CCI779, which has been suggested to inhibit the AKT signaling pathway, probably through inhibition of mTOR (target of rapamycin), a potential target of AKT [reviewed in ref.