Example sentences for: akt

How can you use “akt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Tumors that were Wnt-1 TG, Pten +/- with LOH displayed staining of phosphorylated AKT (Fig.

  • Constitutive membrane localization of AKT leads to its deregulated activation and can induce oncogenic transformation [ 8, 9].

  • The figure also introduces two derivatives of the 'molecule' icon: a 'dimer' icon (adapted from Kohn [ 6]) to represent dimers such as cyclin D1-Cdk4 and a 'biomolecule' icon as a shorthand to represent catalytically active molecules with both 'concentration' and 'activity' properties (for example the kinases in the mitogen-to-ERK and -Akt kinase cascades).

  • Surprisingly, the staining was patchy, suggesting additional factors may be required for AKT activation.

  • Membrane localization renders AKT permissive to phosphorylation by phosphatidyl inositol-dependent kinases, PDK1 and PDK2, at Thr308 within the activation loop and at Ser473 near the carboxyl terminus.


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