Example sentences for: akt

How can you use “akt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This glioma is deficient in PTEN and shows constitutive activation of Akt, which can be inactivated by re-introduction of PTEN [ 47 ] .

  • Phosphorylation activates the kinase domain of AKT, which, in turn, phosphorylates target proteins on serine and threonine residues.

  • Several apoptotic pathways may be inhibited upon activation of AKT, promoting maintenance and survival of tumor cells.

  • As expected, phosphorylated AKT was undetectable in hyperplastic ducts, in tumors from Wnt-1 TG, Pten +/+ mice, and tumors from Wnt-1 TG, Pten +/- mice that retained the wild type allele (Fig.

  • Although it is often assumed that elevated Akt activity is responsible for the increased survival of cancer cells, Akt activity is not the only pathway that is essential for cell survival.


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