Example sentences for: akxd

How can you use “akxd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Second, although D2 and AKXD28 strains demonstrate similar magnitudes of IOP, AKXD28 mice develop more severe and more extensive retinal damage and are more prone to optic nerve head excavation than D2 mice.

  • The mouse strains used in this study were DBA/2J (D2), AKXD-28/Ty (AKXD28), and C57BL/6J (B6).

  • AKXD28 mice contain D2 derived alleles for markers Mtv23 and D6Nds3 which are located approximately 9.5 cM proximal and 5 cM distal to ipd , respectively [ 12, 22, 23].

  • Strikingly, all old AKXD28 mice have severe retinal ganglion cell loss typically associated with severe optic nerve excavation, whereas, few old D2 mice have severe RGC loss and optic nerve excavation is rarely, if ever severe (defined here as extending to a level out side of the inner nuclear layer).

  • In our studies, the occurrence of outer retinal damage was only observed in old AKXD28 eyes with late stage disease, typically several months after signs of glaucoma were evident, and was a late consequence of disease progression.


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