Words similar to upa
Example sentences for: upa
How can you use “upa” in a sentence? Here are some example sentences to help you improve your vocabulary:
This indicates that Glu351 is not essential for the interaction with tPA, but it is an very important determinant for the optimal interaction with uPA, thrombin and plasmin.
For example, positively charged amino acids in the variable region of tPA, uPA and thrombin play dominant roles in the specific interaction with PAI-1.
The smad7 gene contains a perfect palindromic Smad binding element (GTCTAGAC) while the pai-1 and the pthrp promoters harbor AGAC tandem repeats [ 19 33 ] which binds Smad proteins less efficiently [ 34 ] . The upa gene contains only an AP1-binding site which resembles the Smad3/4-responsive AGAC motif [ 35 ] . A weaker binding site could require Smad3 to be present at higher concentrations for efficient binding and would make TGFβ-dependent transcription from a gene more vulnerable to reduced nuclear accumulation of the Smad3 protein.
1 μg/ml) was incubated at 37°C for 30 min with same amount of wtPAI-1, E351A and E351R in term of inhibitory activity toward uPA (20 U in the concentration range of 4-10 μg/ml) in absence or presence of vitronectin (60 μg/ml).
The inhibitory activities of wtPAI-1 and mutants were measured by a direct chromogenic assay using uPA (100 U/μg) and substrate S-2444.
Loading...