Example sentences for: upa

How can you use “upa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This example illustrates how functional relationships that could not be deduced from gene names were uncovered through the analysis of patterns of term occurrence: matrix metalloproteinases (MMP1, 10, 14) and urokinase plasminogen activator (UPA, SPARC) are matrix-interacting molecules involved in tumor invasion and metastasis.

  • Subsequently, the residual PAI-1 inhibitory activity was determined by titration of aliquots on uPA, using S2444 as substrate.

  • Incubation of blood with 1 mg/ml uPA delayed coagulation significantly (by several minutes).

  • TGFβ induced pai-1 mRNA was reduced to approximately 50% by the SB inhibitor, whereas TGFβ-mediated expression of PTHrP and uPA was highly sensitive to SB-203580 treatment.

  • PN-1 has four known target proteases: urokinase plasminogen activator (uPA), tissue type plasminogen activator (tPA), thrombin and trypsin [ 17 ] . Evidence exists for a role of both trypsin [ 18 19 ] and uPA [ 20 21 ] in migratory processes.


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