Example sentences for: upar

How can you use “upar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Systemic and local delivery of an adenovirus encoding ATF have been shown to inhibit the growth of primary tumour implants as well as of tumour metastasis in different animal models [ 18 19 ] . In the ATF-BPTI chimeric protein, ATF has two functions (1) the anti uPA effect with its known angiostatic activity and (2) delivery of BPTI at the tumour site due to over-expression of uPAR on tumour and endothelial cells.

  • A high level of uPAR at the invasive edge of the tumour concentrates uPA where neoangiogenesis occurs [ 12 ] , generating the full activation of the MMP cascade [ 13 ] . Furthermore, various cellular migrations proceed upon the transient attachment of the uPAR to matrix components (e.g.

  • ATF is the N-terminal part of the uPA (residues 1-135) that binds to the uPA receptor (uPAR) and thus inhibits the formation of the uPA-uPAR complex.

  • Other examples of consistency between our microarray results on receptors and the HIV-1 Tat literature, include the down-regulation of gene expression in uPAR (Acc# X74039), IP3 (Acc# D26070, D26351), Glu R flop (Acc# U10302), PPAR (Acc# L07592), alpha-2 macroglobulin receptor protein (Acc# M63959), and receptor tyrosine kinase (Acc# L36645, U66406) genes.

  • The receptor of ATF-BPTI (uPAR) is known to be principally present at the outer edge of the tumour mass and as the volume increases, the proportion of uPAR in the tumour will decrease.


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