Words similar to upar
Example sentences for: upar
How can you use “upar” in a sentence? Here are some example sentences to help you improve your vocabulary:
Systemic and local delivery of an adenovirus encoding ATF have been shown to inhibit the growth of primary tumour implants as well as of tumour metastasis in different animal models [ 18 19 ] . In the ATF-BPTI chimeric protein, ATF has two functions (1) the anti uPA effect with its known angiostatic activity and (2) delivery of BPTI at the tumour site due to over-expression of uPAR on tumour and endothelial cells.
uPAR: Urokinase Receptor
The transmembranous urokinase-type plasminogen activator receptor (uPAR; CD87) focuses the formation of active plasmin at the cell surface, thus enhancing directional extracellular proteolysis.
In contrast, uPAR has been shown to regulate plasminogen-mediated extracellular proteolysis during angiogenesis [ 21 ] .
A high level of uPAR at the invasive edge of the tumour concentrates uPA where neoangiogenesis occurs [ 12 ] , generating the full activation of the MMP cascade [ 13 ] . Furthermore, various cellular migrations proceed upon the transient attachment of the uPAR to matrix components (e.g.
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