Words similar to up-regulation
Example sentences for: up-regulation
How can you use “up-regulation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Recent studies have proposed that myocyte loss incardiomyopathy can occur by apoptosis without an inflammatory response [reviewedin [ 1 2 3 ] ]. In heart failure,growth stimulation initially occurs as a compensatory effort tomeet chronically altered hemodynamic demands and is mediated by systemicand/or local up-regulation of mediators of adrenergic pathways andby various cytokines [ 4 5 ] . However, cytokinescan be directly toxic to cardiac myocytes and result in increasedapoptotic cell death [ 3 6 ] . Local up-regulationof angiotensin II induces immediate-early genes, which may leadto increased protein synthesis and myocardial hypertrophy or, alternatively,may up-regulate expression of apoptotic proteins (such as p53) incardiac myocytes.
The results of this study open up further avenues of investigation with respect to the role of the mucus layer in causing a secondary up-regulation of IBAT expression and function.
During rod outer segment ingestion, there is a generation of H 2 O 2 [ 2 3 ] and an up-regulation of PPARγ mRNA expression [ 24 ] in RPE, experiments were performed to determine if H 2 O 2 could induce PPARγ protein expression over the control levels.
S. aureus caused a rapid and sustained up-regulation of TRAIL mRNA and TRAIL protein expression.
We then introduced into each line a plasmid containing a luciferase reporter downstream of multimerized Gli binding sites and a minimal promoter [ 20 ] . An isolated stable clone of the 10T1/2 cell transfectants (referred to as clone S12) gave a 10-20-fold up-regulation of luciferase activity (Figure 1a) when stimulated with Hh protein [ 21 ] for 24 hours.