Example sentences for: up-regulates

How can you use “up-regulates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It was found that the major surface glycoprotein of P. carinii up-regulates the expression of integrins on the surface of cultured lung cells [ 1] to facilitate this attachment.

  • This would imply that Tat up-regulates many ribosomal genes that may be necessary to produce functional ribosomes needed for viral mRNA translation.

  • LIF and LIFR are functionally expressed in rodent tissues that are central to GC production: the hypothalamus [ 8 ] and pituitary [ 9 10 11 12 ] . LIF works in synergy with corticotropin-releasing hormone (CRH) in the hypothalamus to increase pituitary pro-opiomelanocortin (POMC) and, ultimately, pituitary adrenocorticotrophin hormone (ACTH) [ 9 11 13 14 15 16 ] . LIF also stimulates POMC gene expression directly in the pituitary [ 9 11 15 17 ] . LIF up-regulates pituitary prohormone convertase (PC1).


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