Words similar to up-regulated
Example sentences for: up-regulated
How can you use “up-regulated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Examples include RPs L7a, L37 and S14 in prostate tumors and cell lines [ 20 ] ; RPs L5, L7A, L18, S3, S6, S8, S12, S13, S28, P0 and P1 in colorectal cancers and cell lines [ 21 22 23 24 25 26 ] ; L5 in astrocytomas [ 27 ] ; L18a in squamous cell carcinoma [ 28 ] ; L19 in breast tumors that over-express erbB-2 [ 29 ] ; RPs S3A, S4, and S17 in lymphoid malignancies [ 30 ] ; L38, S4, P0, and P1 in rhabdomyosarcoma cell lines [ 31 ] ; and P0, P1, P2, L5, L9, L35, L39, S3A, S10, and S17 in liver tumors [ 32 ] . In addition, as noted above, a recent SAGE study identified targets of N-myc in a human neuroblastoma cell line [ 18 ] . Of 114 up-regulated genes detected, 66 encoded RPs with elevations ranging from 40% to 37-fold.
Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are nuclear transcription factors that mediate the action of retinoids [ 11 12 ] . We have demonstrated that in the rat, castration resulted in an increase in mRNAs for RAR α and γ in the prostate; such effects were prevented by T replacement [ 13 ] . We also demonstrated that the levels of mRNAs for RAR α and γ in non-tumorigenic rat epithelial cells (NRP152) were down-regulated, whereas those in tumorigenic cells (NRP154) were unaffected or up-regulated following T treatment [ 14 ] . In addition, RAR α was over-expressed in tumorigenic NRP154 cells.
It seems the two algorithms have very close performance Table 1. They all have greater error margins for calculating down-regulated fold changes (captured by R err2 ) than up-regulated ones (captured by R err1 ). MAS4 is more asymmetric than MOID in this aspect.
Among the adhesion molecules up-regulated in IBD, MAdCAM-1, the mucosal cell adhesion molecule, is thought to be preeminent in the development of chronic gut inflammation.
It is interesting to note that Cdc2 (Acc# X05360), Cdc10 homolog (Acc# S72008), and Cdc37 (Acc# U43077) were all up-regulated in Tat expressing cells.
Loading...