Words similar to up-regulated
Example sentences for: up-regulated
How can you use “up-regulated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Several recent papers identify genes that are up-regulated by cell density.
For example, RP L18, which was significantly down-regulated by NGF, has been reported to negatively regulate double-stranded RNA (dsRNA)-activated protein kinase (PKR) [ 45 ] . As an additional example RP S19, which is also down-regulated by NGF, has been implicated in erythropoiesis and has also been described as a monocyte chemotactic factor [ 46 ] . As one last example, rat RP L9 which we found to be up-regulated by NGF starting within a few hours and maximally by 8 hrs, has been shown to be the ortholog of the yeast gene grc5 which appears to be involved in multiple cellular functions including growth control, cytoskeleton control and energy metabolism [ 47 ] . Identification of NGF-regulated RPs should now facilitate exploration of their potential roles in the responses of cells to neurotrophins.
Caspase 6 is activated by active Caspase 3 and in turn cleaves lamin, resulting in nuclear membrane fragmentation [ 55 ] . FAF interacts with the cytoplasmic domain of the Fas receptor to potentiate Fas-mediated apoptosis [ 56 57 ] . Thus, the up-regulated cell cycle inhibitors and apoptotic proteins clearly favor cell cycle arrest and death.
However, with ADGE microarray, there were 63 genes >4 fold up-regulated, 220 genes 2-4 fold up-regulated, 92 genes 2-4 fold down-regulated and 14 genes >4 down-regulated.
Applying the restriction fingerprints of the above mentioned single clone analysis, we found several genes that were up-regulated in wounds of dexamethasone treated animals.
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