Example sentences for: translocated

How can you use “translocated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Smad1 is translocated from the cytoplasm to the nucleus upon its activation by the BMP type I receptors [ 40 ] . The physical interaction between Smad1, Az and HsN3 suggests that BMP signaling might regulate the intracellular localization of Az and HsN3.

  • Once bound to the proteasome, a polyubiquitinated substrate can be unfolded by the RP and irreversibly translocated into the CP.

  • Upon treatment of these cells with dexamethasone (500 nM for 30 minutes) the GR-GFP efficiently translocated to the nucleus.

  • Released NF-κB dimers then translocate to the nucleus, bind to its cognate DNA elements, and induce the expression of target genes [ 23 24 25 ] . Activated, nuclear translocated, NF-κB transcription factor has been documented in the mouse embryo from the 1-cell stage onward [ 26 27 ] . Activated NF-κB translocation into the nucleus, directly or indirectly, effects the transcriptional control of over 150 target genes [ 28 ] . NF-κB enhances cell proliferation by stimulating the expression of cytokines such as TNF, IL-1, IL-2, IL-6, and IL-8, among others [ 28 29 ] ; NF-κB inhibits apoptosis by inducing TRAF and clAP expression which suppresses Caspase 8 activation [ 30 ] , and by inhibition of p53 transactivation [ 31 32 ] .

  • Upon addition of 1 μM dexamethasone (Dex) the receptor is translocated into the nucleus within 10 min [ 48 ] . When GR-GFP was co-expressed with the wild-type Rab24 in NIH3T3 cells, we observed normal ligand-dependent translocation of GR-GFP into the nucleus when Dex was applied (Fig.


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