Example sentences for: translocate

How can you use “translocate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Location of the insertion was not determined but the LCR phenotype and ability to translocate Yops into HeLa cells was verified (data not shown).

  • By forming a multimeric complex with the Co-Smad Smad4, activated R-Smads translocate to the nucleus and induce transcriptional modulation of target genes [ 8 ] .

  • Released NF-κB dimers then translocate to the nucleus, bind to its cognate DNA elements, and induce the expression of target genes [ 23 24 25 ] . Activated, nuclear translocated, NF-κB transcription factor has been documented in the mouse embryo from the 1-cell stage onward [ 26 27 ] . Activated NF-κB translocation into the nucleus, directly or indirectly, effects the transcriptional control of over 150 target genes [ 28 ] . NF-κB enhances cell proliferation by stimulating the expression of cytokines such as TNF, IL-1, IL-2, IL-6, and IL-8, among others [ 28 29 ] ; NF-κB inhibits apoptosis by inducing TRAF and clAP expression which suppresses Caspase 8 activation [ 30 ] , and by inhibition of p53 transactivation [ 31 32 ] .

  • To explain the TGFβ 1 sensitivity of SMAD4-deleted cells, it is speculated that after binding of TGFβ 1 to its receptor, activated SMAD2/3 may translocate to the nucleus and activate gene expression even in the absence of SMAD4.

  • This means that proteins with a small number of TM-helices must oligomerize to form a proper tunnel to translocate molecules through the membrane.


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