Example sentences for: transgenic

How can you use “transgenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In order to produce such a model for studying the effects of Pten mutations in breast cancer, we have crossed Wnt-1 TG mice to mice heterozygous for Pten . Mice transgenic for MMTV- Wnt-1 and heterozygous for Pten developed mammary adenocarcinomas much earlier than mice carrying either lesion alone.

  • For example, PGMinvrpt(3)76 is PGMinvrpt construct inserted on chromosome 3, independent transgenic line 76.

  • Thus in our transgenic animals, aberrant Wnt activation appears to be limited to mature, postmitotic neurons.

  • Similar results were reported for this FLAG epitope-tagged mutant in other cell lines [ 26 ] . Second, the tail kinking and "waltzing" phenotypes in our transgenic animals expressing stabilized human β-catenin are highly similar to those seen in Fused mice [ 29 ] . Fused encodes the murine Axin homologue, and mutation of this gene results in activation of Wnt signaling [ 30 ] . The tail kinking in our animals presumably results from low level expression of the mutant transgene in utero during vertebral patterning.

  • Because others have also reported competitive titration by transgenic sequences in C. elegans [ 26, 32], we expect that it will not be uncommon.


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