Words similar to transgene
Example sentences for: transgene
How can you use “transgene” in a sentence? Here are some example sentences to help you improve your vocabulary:
This can result in ectopic expression of the transgene because both copy number and the site integration can influence transgene expression.
In contrast to the ubiquitous DDRP, cellular RDRPs that are involved in PTGS so far have been detected only in eukaryotes [ 1 26 ] . The PTGS phenomenon covers a variety of complementarity-dependent silencing pathways, such as RNA interference (RNAi) in animals and slime mold, co-suppression (silencing of transgene and the corresponding endogenous genes) and virus gene resistance in plants, and quelling in fungi, all of which share a common mechanism of RNA turnover [ 28 37 38 39 40 ] . Essentially, double-stranded (ds) RNA, which is formed in these processes, triggers the activation of a sequence-specific RNA degradation system, which targets homologous RNAs [ 41 42 ] . The dsRNA is broken down by the Dicer enzyme into 21-25 nucleotide (nt) fragments called small interfering RNA or siRNAs [ 43 44 45 ] . The siRNAs subsequently associate with a complex of proteins called RISC and target homologous RNA by serving as guides for multiple rounds of RNA cleavage [ 45 46 ] .
LOH at the Pten locus has recently been reported in mammary tumors arising in Pten heterozygous mice [ 26], but only 4% of the mice developed tumors before the age of 30 weeks, and, in our cross, none of the Pten +/- mice without the Wnt-1 transgene had a palpable mammary tumor before the age of 30 weeks.
The introduction of the hCARΔcyt.CD2 transgene into TCR transgenic lines, such as the DO11.
Moreover, it ensures that a single copy of the transgene is introduced into a defined genomic location.
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