Example sentences for: transgenes

How can you use “transgenes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Over-expression and ectopic expression of transgenes, as well as the expression of genetic variants, has facilitated the deciphering of complex cellular processes as well as the generation of animal models of disease.

  • It is informative to compare the epigenetic interactions of the 35S:GFP-COP1 transgenes with those of the PAI (trans)genes, the only other well-characterized system in Arabidopsis [ 12 ] . Both gene sets consist of relatively simple repeat structures and singlet loci, which reside in essentially single-copy environments of Arabidopsis ( [ 27 ] and unpublished observations).

  • In sum, the availability of tetraploid aggregation-competent ES cells that support targeting of transgenes to the hprt locus should facilitate the rapid analysis of transcriptional regulatory elements in vivo as well as the phenotypic characterization of alleles that are incompatible with normal development.

  • These data confirm the extraordinary efficiency of using this approach to target transgenes to a marked genomic locus.

  • However, it is only suitable for introduction of transgenes to the HPRT locus and, in addition, requires the availability of HPRT-negative ES cell lines.


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