Words similar to tpa

Example sentences for: tpa

How can you use “tpa” in a sentence? Here are some example sentences to help you improve your vocabulary:

Complex formation of the fibrosarcoma PAI-1, wtPAI-1 or its mutants with single-chain tPA or uPA were performed as described earlier [ 20 ] . Samples of PAI-1s (5 U) were incubated in the absence or in the presence of a 2-fold excess of uPA or tPA in the activity assay buffer.
In addition, it is known that PAI-1 inhibits either tPA or uPA by forming a 1:1 SDS stable complex [ 4 ] , wtPAI-1 indeed could form SDS stable complex with tPA or uPA (Fig.
The interaction of Glu351 with uPA is much more important than that of Glu351 with tPA, which is demonstrated by improved reactivity of Glu351 mutants toward uPA, but not toward tPA, showing that tPA is not directly interact with Glu351 of PAI-1, whereas Glu351 is necessary for the optimal interaction with uPA.
[ 10 ] demonstrated a retardation of granule cell migration in tissue plasminogen activator (tPA) knock-out mice.
With single mutation at position Glu351, we improved reactivity of PAI-1 to thrombin and plasmin without significantly affecting its specificity to tPA.