Words similar to tpa

Example sentences for: tpa

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The rate constants of tPA for wtPAI-1, Glu351Ala and Glu351Arg were similar (Table 4), however, The rate constants of inhibition toward uPA by Glu351Ala and Glu351Arg were 4 and 7-fold higher than by wtPAI-1, respectively.
In order to prove that p44/42 MAPK can be stimulated in H441 cells by an activator of this kinase, some cells were also treated with 10 nM 12- O -tetradecanoylphorbol-13-acetate (TPA), a strong stimulator of p44/42 MAPK in H441 cells, for 5 min [ 21 ] . TPA caused an approximately twofold increase in p44/42 MAPK phosphorylation over control levels.
The second-order rate constants for the interaction of the fibrosarcoma PAI-1, wtPAI-1 or the indicated mutants with single-chain tPA or uPA were determined in a single-step assay as previously described.
tPA, tissue-type plasminogen activator; uPA, urokinase-type plasminogen activator; PAI-1, plasminogen activator inhibitor type 1; serpin, serine protease inhibitor; RCL, reactive center loop; Vn, vitronectin, SDS, sodium dodecylsulfate; PAGE, polyacrylamide gel electrophoresis.
These results show that the wtPAI-1 could inhibit tPA or uPA at the same rate as the fibrosarcoma PAI-1.