Example sentences for: tpa

How can you use “tpa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We showed that rapid stimulation of HUVEC with thrombin, PMA, TPA or AGT II or overnight stimulation with TNFα or LPS does not induce release of annexin V-binding membrane MP.

  • [ 10 ] demonstrated a retardation of granule cell migration in tissue plasminogen activator (tPA) knock-out mice.

  • Confluent HUVEC were washed with HBSS and incubated for 30 min at 37°C with various agonists in HBSS with 0.35%BSA: HBSS alone; 0.5 % dimethyl sulfoxide (DMSO); ionophore A23187 1-100 μmol/L; phorbol myristate acetate (PMA) 1 μg/mL; human thrombin receptor activating peptide SFLLRNP (TRAP) 1-50 μmol/L; human thrombin (THR) US FDA standard lot J (Bethesda, MD) 0.1-10 NIH Unit/mL; human tissue plasminogen activator (TPA) 3.5 kU/mL or human angiotensin II (AGTII) 1 μmol/L.

  • The catalytic center of tPA interacts with the reactive site of PAI-1 with concominant formation of 1:1 molar, SDS-stable complex.

  • For example, positively charged amino acids in the variable region of tPA, uPA and thrombin play dominant roles in the specific interaction with PAI-1.


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