Example sentences for: tpa

How can you use “tpa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • AGTII, angiotensin II; BSA, bovine serum albumin; CHX, cycloheximide; CPT, camptothecin; DMSO, dimethyl sulfoxide; FITC, fluorescein isothiocyanate; HBSS, Hanks' balanced salt solution; HUVEC, human umbilical vein endothelial cells; IC-IgG, IgG isotype control; Mab, monoclonal antibody; MP, microparticles; PE, phycoerythrin; PI, propidium iodide; PMA, phorbol-myristate-acetate; PS, phosphatidylserine; TRAP, thrombin receptor activating peptide (SFLLRNP); TNF, tumor necrosis factor; TPA, tissue plasminogen activator; TUNEL, terminal deoxynucleotidyltransferase dUTP nick end labeling; ZVAD, Z-Val-Ala-Asp-fluoromethyl ketone.

  • Interestingly, there was no significant difference between the mutants tested and the wtPAI-1 in their ability to inactivate either tPA or uPA (Table 3).

  • More importantly, Glu351 of PAI-1 is a specificity determinant for uPA, thrombin and plasmin, but not for tPA.

  • The second-order rate constants for the interaction of the fibrosarcoma PAI-1, wtPAI-1 or the indicated mutants with single-chain tPA or uPA were determined in a single-step assay as previously described.

  • To induce macrophage differentiation, 10 nM phorbol ester (TPA) was added to growth cultures at a cell density of 1.5 × 10 6cells/ml, 40 hrs prior to harvest.


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