Example sentences for: tpa

How can you use “tpa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Complex formation of the fibrosarcoma PAI-1, wtPAI-1 or its mutants with single-chain tPA or uPA were performed as described earlier [ 20 ] . Samples of PAI-1s (5 U) were incubated in the absence or in the presence of a 2-fold excess of uPA or tPA in the activity assay buffer.

  • We showed that rapid stimulation of HUVEC with thrombin, PMA, TPA or AGT II or overnight stimulation with TNFα or LPS does not induce release of annexin V-binding membrane MP.

  • PN-1 has four known target proteases: urokinase plasminogen activator (uPA), tissue type plasminogen activator (tPA), thrombin and trypsin [ 17 ] . Evidence exists for a role of both trypsin [ 18 19 ] and uPA [ 20 21 ] in migratory processes.

  • Complete linkage clustering based on Euclidean distance [ 23 ] of these four sets of transcripts (cytosolic versus cytoskeleton transcripts in HL-60 cells in the presence or absence of TPA) revealed that the cytoskeleton-anchored population in the precursor HL-60 cells and those in the macrophage cells were most similar (Fig.

  • This indicates that Glu351 is not essential for the interaction with tPA, but it is an very important determinant for the optimal interaction with uPA, thrombin and plasmin.


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