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Example sentences for: trnas

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However, since the information on the Glycine-, Histidine- or Glutamine-isoacceptor tRNAs in mouse is not yet available (see M. Sprinzl, K.S.
Since rare tRNAs generally correspond to rare codons [ 27], we checked whether a bias in codon usage was correlated with readthrough efficiency.
In yeast and mammalian cells, GCN2 is a protein that senses amino acid starvation and brings about altered cell physiology in response to such starvation [ 24 25 ] . GCN2 is a protein kinase that phosphorylates the α subunit of the translation initiation factor eIF2 [ 26 ] . The GCN2 protein from yeasts, Drosophila , and mammals is composed of three domains: a pseudokinase domain that may function as a regulatory domain, a kinase domain, and a HisRS domain that shares significant similarity to histidyl-tRNA synthetases [ 27 28 29 30 ] . Studies of yeast GCN2 revealed that the HisRS domain binds uncharged tRNAs that accumulate when cells are starved for amino acids [ 31 32 ] . As a result the kinase domain is activated and phosphorylates eIF2α at Ser51.
E. coli has 86 tRNAs, and most of these appear to be present in the ancestor (the parsimony criterion for presence of a tRNA in the ancestor, based on distribution in sequenced genomes, is somewhat unreliable because of sequence homology among different tRNA genes).
Buchnera has only 32 tRNAs, with most amino acids having only one.