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Example sentences for: trnas
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Along these lines, when the aminogylcosides (kanamycin, hygromycin B, paromycin and neomycin) due to their ability to inhibit protein synthesis by affecting ribosomal fidelity, or puromycin because of its competing ability with tRNAs for binding on the large ribosomal subunit, or cycloheximide which inhibit the large ribosomal subunit by preventing ribosomal movement along the mRNA, were used in active HIV-1 infection, it was found that both cycloheximide and puromycin produced the greatest decrease in HIV-1 inhibition, presumably by inhibiting the large subunit of the ribosome [ 41 ] .
Based on the normal function of GCN2-like proteins [ 25 ] , these findings suggest that uncharged tRNAs are more prevalent within the cells during this time relative to either growing cells or to cells immediately after removal of the food source.
The Buchnera gene inventory, consisting of only 564 ORFs, 32 tRNAs and a single copy of each rRNA gene, is essentially a subset of that of E. coli [ 8].
Assuming that the ancestor had the same complement of tRNAs as E. coli, 15 were lost from within syntenic fragments and 39 were lost in regions between syntenic fragments.
Release 1 reported 292 tRNAs [ 3]; two tRNA genes were deleted as a result of sequence finishing resolving repeated regions of the genome.