Example sentences for: tpr

How can you use “tpr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A similar change in susceptibility to proteolysis upon lipid binding was observed with PP5 [ 19 ] . As with PP5, only lipids that stimulated 32P-MBP dephosphorylation slowed degradation of the 20 kDa TPR fragment (Table 1).

  • AA did not stimulate 32P-MBP dephosphorylation by Ppt1p after removal of the TPR domain (data not shown).

  • Removal of the TPR domain prevents stimulation by lipid, but only modestly increases Ppt1p activity.

  • Removal of the TPR domain of PP5 by limited proteolysis increases enzyme activity and the TPR domain binds lipid [ 7 8 9 19 20 ] . Using conditions similar to those employed with PP5, digestion of Ppt1p with trypsin in the absence of lipid produced a 44 kDa catalytic fragment that was stable for at least 30 min and a 20 kDa fragment that was degraded within 30 min (Fig.

  • Although more work will be required to determine its role in lipid stimulation, removal of the TPR domain had only a small effect on Ppt1p activation.


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