Example sentences for: topological

How can you use “topological” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Simulation studies have shown that incomplete taxon sampling does not increase topological errors, and that most error is caused by limited sequence data [ 18 ] .

  • Here multiple groups predicted large parts of a few protein sequences at a crude topological level (within 6.0 Å C α RMSD for ≈ 60 residues) [ 22 ] .

  • Nash found a way of applying this to the domain of all game strategies so that the guaranteed fixed point was the equilibrium for the game--clever, but the earlier topological theorem did all the work.

  • The predicted topological organization consists of six transmembrane domains with a hydrophobic loop between the fifth and sixth domain which lines the ion conducting pore [ 17 ] . VR1 has been expressed heterologously in several cell lines and has intrinsic sensitivity to thermal stimuli and to capsaicin (a pungent extract of the Capsicum pepper family) [ 18 ] . VR1 does not discriminate among monovalent cations [ 19 ] ; however, it exhibits a notable preference for divalent cations with a permeability sequence of Ca 2+> Mg 2+> Na +≈ K +≈ Cs + [ 9 ] . Ca 2+is especially important to VR1 function, as extracellular Ca 2+mediates desensitization [ 20 21 ] , a process which enables a neuron to adapt to specific stimuli by diminishing its overall response to a particular chemical or physical signal.

  • Even though our all-atom function is readily able to distinguish native-like conformations in certain scenarios, it is not adequate for large sets of decoys where the closest conformation generated is represented at the topological level (≈ 6.0 Å C α RMSD relative to the experimental result).


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