Example sentences for: topoisomerase

How can you use “topoisomerase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The presence of this decatenation loop instead of the Zn(II) binding ZD domain in topoisomerase III may account for the dominance of the decatenation activity over the relaxation activity.

  • We further focused our study on MP-release from HUVEC after proapoptotic stimulation with the topoisomerase I inhibitor camptothecin (CPT).

  • Top67 can recognize cleavage sites preferred by E. coliDNA topoisomerase I

  • It has previously been observed that a mutation in the Zn(II) binding motif can affect the cleavage site selectivity of topoisomerase I [ 32 ] even though Top67 by itself can recognize both the cytosine in the -4 position and the junction of single- and double-stranded DNA.

  • This hypothesis could be tested using other DNA topoisomerase poisons known to induce NF-κB [ 34].


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