Words similar to topoiiα
Example sentences for: topoiiα
How can you use “topoiiα” in a sentence? Here are some example sentences to help you improve your vocabulary:
MCF7/WT cells expressed a high level of TopoIIα only: P-gp and GSTπ protein expression were undetectable.
We also observed the expression of the non-P-gp MDR-related genes GSTπ, TopoIIα and MRP.
ADR = adriamycin; DRO = droloxifen; GSTπ = glutathione S-transferase Pi; MDR = multidrug resistance; MG = megestrol; MRP = MDR-related protein; MTT = 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2 H -tetrazolium bromide; NOM = nomegestrol; PBS = phosphate-buffered saline; P-gp = P-glycoprotein; RT-PCR = reverse transcriptase polymerase chain reaction; TAM = tamoxifen; TopoIIα = topoisomerase IIα; VRP = verapamil.
No marked difference whose TopoIIα protein expression was found before and after NOM treatment in either MCF7/ADR or MCF7/WT cells.
In brief, after three washes with phosphate-buffered saline (PBS), fixed cells in each smear were layered with the primary antibody against P-gp (1:20 dilution), GSTπ (1:25 dilution) and TopoIIα (1:50 dilution) and incubated overnight (a minimum of 18 h).