Example sentences for: topoiiα

How can you use “topoiiα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • MCF7/WT cells expressed a high level of TopoIIα only: P-gp and GSTπ protein expression were undetectable.

  • We also observed the expression of the non-P-gp MDR-related genes GSTπ, TopoIIα and MRP.

  • ADR = adriamycin; DRO = droloxifen; GSTπ = glutathione S-transferase Pi; MDR = multidrug resistance; MG = megestrol; MRP = MDR-related protein; MTT = 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2 H -tetrazolium bromide; NOM = nomegestrol; PBS = phosphate-buffered saline; P-gp = P-glycoprotein; RT-PCR = reverse transcriptase polymerase chain reaction; TAM = tamoxifen; TopoIIα = topoisomerase IIα; VRP = verapamil.

  • No marked difference whose TopoIIα protein expression was found before and after NOM treatment in either MCF7/ADR or MCF7/WT cells.

  • In brief, after three washes with phosphate-buffered saline (PBS), fixed cells in each smear were layered with the primary antibody against P-gp (1:20 dilution), GSTπ (1:25 dilution) and TopoIIα (1:50 dilution) and incubated overnight (a minimum of 18 h).


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