Words similar to topo
Example sentences for: topo
How can you use “topo” in a sentence? Here are some example sentences to help you improve your vocabulary:
We used human insulin cDNA (320 bp) cloned in plasmid pCR4-TOPO (Invitrogen) as a template for in vitro transcription to produce riboprobes with a digoxigenin-RNA labeling kit (Ambion, Austin, Texas, United States), performed hybridization with IPC cluster sections as described [16], and used DIG Nucleic Acid Detection Kit (Roche, Indianapolis, Indiana, United States) for development according to the manufacturer's instructions.
DNA Topo I is an essential enzyme involved in such crucial cellular functions as replication and transcription.
We have focused on the effects of the leading Topo I inhibitor, CPT, on collagen production by dermal fibroblasts obtained from patients with SSc.
This study was undertaken to determine whether inhibition of its activity by noncytotoxic doses of CPT, a drug that selectively targets Topo I, could reverse the activated phenotype of fibroblasts from patients with SSc.
It is commonly used in in vitro experimental model systems to study the mechanisms of action of Topo I inhibitors.
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