Words similar to topo

Example sentences for: topo

How can you use “topo” in a sentence? Here are some example sentences to help you improve your vocabulary:

anti-Topo I = anti-topoisomerase I; BSA = bovine serum albumin; CAT = chloramphenicol acetyltransferase; COL1A2 = type α2(I) collagen; CPT = camptothecin; DMEM = Dulbecco's modified Eagle's medium; ELISA = enzyme-linked immunosorbent assay; FBS = fetal bovine serum; GAPDH = glyceraldehyde-3-phosphate dehydrogenase; SEM = standard error of the mean; SSc = systemic sclerosis; Topo I = topoisomerase I.
We have focused on the effects of the leading Topo I inhibitor, CPT, on collagen production by dermal fibroblasts obtained from patients with SSc.
The circulating anti-topoisomerase-I (anti-Topo I; Scl-70) antibodies are highly specific for SSc [ 6], and they are found in sera from 30 to 70% of patients [ 7].
The eluted solution containing single strand, SSR-enriched fragments was cloned into the pCR4-TOPO vector, and the recombintants were transformed to TOP10 Chemically Competent E. coli following the instruction of TOPO TA Cloning kit (Invitrogen, San Diego, CA).
Camptothecin (CPT) and its derivatives specifically target Topo I by binding noncovalently to these cleavable complexes, stabilizing them and interfering with DNA religation [ 11].