Example sentences for: topo

How can you use “topo” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because of the potential pathogenic role of Topo I in SSc, we undertook this study to evaluate the utility of noncytotoxic concentrations of Topo I inhibitors for the treatment of SSc.

  • Human DNA topoisomerase I (Topo I) is a 765-amino-acid nuclear enzyme [ 9] involved in topological changes of DNA structure [ 10].

  • The nucleotide sequences of these genes contain specific DNA motifs that constitute high-affinity Topo I binding sites [ 31].

  • Clinically approved Topo I inhibitors, irinotecan and topotecan, are semisynthetic derivatives of CPT that differ from CPT in toxicity profiles and water solubility but not in the mechanisms of action [ 16, 17].

  • DNA Topo I is an essential enzyme involved in such crucial cellular functions as replication and transcription.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast