Words similar to tgfβ-induced

Example sentences for: tgfβ-induced

How can you use “tgfβ-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

The delayed TGFβ-mediated entry of Smad3 into the nucleus in the presence of SB-203580 prompted us to examine the effect of SB-203580 on TGFβ-induced gene expression in a time-course experiment.
Here we report that two small molecules, SB-202190 and SB-203580, diminished TGFβ-induced expression of TGFβ target genes which was accompanied by a perturbation of TGFβ-mediated Smad3 nuclear accumulation, a crucial step in TGFβ signal transduction.
SB-202190 and SB-203580 deregulate TGFβ-induced Smad3 nuclear accumulation
It has recently been shown that SB-202190 and SB-203580 are able to inhibit TGFβ-induced phosphorylation of Smad3 by the TGFβ-receptor I kinase (ALK5) and to interfere with nuclear localization of Smad3 [ 17 ] . Nuclear translocation of Smad3 results directly from TGFβ-induced Smad3 phosphorylation and is, therefore, a measure of the activation status of ALK5.
Next, we studied the time-course of TGFβ-induced Smad3 nuclear entry in the presence or absence of SB-203580.