Words similar to tgfβ-induced

Example sentences for: tgfβ-induced

How can you use “tgfβ-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

ets-1, ets-2 and ese-1/esx . Smad7 was of particular interest as it belongs to the inhibitory Smads, which can counteract TGFβ-induced gene activation [ 23 ] . The response of the smad7 gene to TGFβ is unusually rapid [ 24 ] which is believed to stem from the peculiar nature of the Smad7 promoter that contains a "perfect" Smad binding site [ 25 ] . Another inhibitory Smad protein is Smad6.
The delayed TGFβ-mediated entry of Smad3 into the nucleus in the presence of SB-203580 prompted us to examine the effect of SB-203580 on TGFβ-induced gene expression in a time-course experiment.
Next, we studied the time-course of TGFβ-induced Smad3 nuclear entry in the presence or absence of SB-203580.
Here we report that two small molecules, SB-202190 and SB-203580, diminished TGFβ-induced expression of TGFβ target genes which was accompanied by a perturbation of TGFβ-mediated Smad3 nuclear accumulation, a crucial step in TGFβ signal transduction.
It has recently been shown that SB-202190 and SB-203580 are able to inhibit TGFβ-induced phosphorylation of Smad3 by the TGFβ-receptor I kinase (ALK5) and to interfere with nuclear localization of Smad3 [ 17 ] . Nuclear translocation of Smad3 results directly from TGFβ-induced Smad3 phosphorylation and is, therefore, a measure of the activation status of ALK5.