Words similar to tgfβ-induced

Example sentences for: tgfβ-induced

How can you use “tgfβ-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

The delayed TGFβ-mediated entry of Smad3 into the nucleus in the presence of SB-203580 prompted us to examine the effect of SB-203580 on TGFβ-induced gene expression in a time-course experiment.
2C), which appeared to enhance the amount of both basal and TGFβ-induced nuclear Smad3, a phenomenon that has been reported earlier [ 22 ] .
ets-1, ets-2 and ese-1/esx . Smad7 was of particular interest as it belongs to the inhibitory Smads, which can counteract TGFβ-induced gene activation [ 23 ] . The response of the smad7 gene to TGFβ is unusually rapid [ 24 ] which is believed to stem from the peculiar nature of the Smad7 promoter that contains a "perfect" Smad binding site [ 25 ] . Another inhibitory Smad protein is Smad6.
It is remarkable that a constitutively active form of JNK activator MKK and Smad7 are able to cooperatively downregulate TGFβ-responsive promoters [ 53 ] . It is quite possible that a Smad7/JNK synergistic interaction is involved in the TGFβ-dependent downregulation of Ese-1/Esx expression, where JNK alone might mediate the initiation of the TGFβ-induced repression.
However, both agents failed to reproduce the effect of the SB inhibitors as TGFβ-induced nuclear accumulation of Smad3 was not affected by these inhibitors (Fig.