Words similar to tgfβ

Example sentences for: tgfβ

How can you use “tgfβ” in a sentence? Here are some example sentences to help you improve your vocabulary:

The normal function of transforming growth factor β 1 (TGFβ 1 ) is essential for the entire organism, representing a multifunctional regulator of cell growth and differentiation [ 1 2 3 4 5 ] . TGFβ 1 is a potent inhibitor of epithelial cell proliferation.
In the past, these compounds have been widely used as specific p38 inhibitors [ 12 ] and their inhibitory action has been well documented [ 13 14 15 ] . However, recent results show that, in a comparable concentration range they inhibit the serine/threonine kinase activity of TGFβ type I receptor preventing phosphorylation of R-Smads [ 16 17 18 ] .
For indirect immunofluorescence, 10 4cells were cultured on glass coverslips, stimulated with 10 nM mature TGFβ 1 for 10 minutes, stained as described [ 66 67 ] and viewed using a Zeiss LSM-510 confocal microscope.
Measurements were made of the α-SMA content and apoptotic status of fibroblasts embedded within attached or detached(relaxed) gels incubated for three days in the presence or absence of serum and TGFβ1 (Figs.
In later stages of tumorigenesis, TGFβ can act as a stimulator of invasion and metastasis [ 3 ] acting directly on the tumor cells or inducing angiogenesis and facilitating local and systemic immunosuppression, respectively [ 4 ] . For example, TGFβ may stimulate the expression of proteases such as uPA, MMP-3 or MMP-9, enzymes frequently overexpressed in invasive tumor cells [ 5 6 ] .