Words similar to sts

Example sentences for: sts

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In some experiments, Jurkat cells were incubated for 1 hour in the presence of the pancaspase inhibitor benzylocarbonyl-Val-Ala-Asp-fluromethyl-ketone (zVAD-fmk) (ALEXIS), used at 100 μM, prior to addition of STS.
The caspase family of proteases plays a central role in apoptosis by participating in a cascade of cleavage events that result in the apoptotic phenotype [ 31 ] . We investigated whether the proteolysis of Golgi autoantigens caused by treatment with STS was caspase dependent.
The integrity of native golgin-95 and golgin-97, in which apoptotic fragments were not detected, was almost completely maintained at 12 hours after the addition of STS (data not shown).
While the exact mechanism remains unclear, STS has been shown to initiate caspase driven apoptosis in a manner distinct from chemotherapeutic agents such as cisplatinum, etoposide, and tamoxifen, which directly cause DNA damage and tend to favor ERCC1 activation [ 37 38 ] .
In contrast to the Golgi swelling already described, striking fragmentation of the Golgi complex was observed during necrosis in HEp-2 cells treated with 10 μM STS (Fig.