Words similar to sttype
Example sentences for: sttype
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The 1 sttype III repeat of fibronectin was expressed as a fusion protein coupled to GST, and this GST-3FN1 fusion protein was coupled to Sepharose and used in affinity purification.
For example, the N-terminal 70 kDa region, the 1 sttype III repeat and the 10 thtype III repeat are thought to be important for the proper alignment of fibronectin molecules during matrix assembly [ 15 16 17 18 19 20 21 22 ] . We and others have shown that a recombinant protein representing a portion of the first type III repeat (protein III1-C) can affect fibronectin matrix assembly and cell growth [ 2 3 4 16 ] . Moreover, a mutant recombinant fibronectin molecule that is lacking the first seven type III repeats has been shown to lead to defective fibronectin matrix assembly in cell culture and in vivo, and to inhibition of cell proliferation [ 23 24 ] . Although the matrix produced with fibronectin lacking the first seven type III repeats was somewhat aberrant, this study does show that some matrix assembly can occur without the first type III repeat.