Words similar to srp

Example sentences for: srp

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These include the group I [ 30 31 32 33 ] and II [ 34 35 ] introns, RNase P [ 36 37 38 ] , telomerase RNA [ 39 40 ] , tmRNA [ 41 ] , U RNA [ 42 ] , and the SRP RNA [ 43 ] . The comparative sequence analysis paradigm has been successful in determining structure over this wide range of RNA molecules.
Third, both mtr10 tab 1-1and srp1-31 affect nuclear transport, suggesting that nuclear transport regulates mitotic exit.
Nuclear transport-defective mutations in MTR10 and SRP1 (mtr10 tab 1-1and srp1-31, respectively) bypassed cdc15Δ.
Mtr10 assembles with and functions as a nuclear import receptor for the mRNA-binding protein Npl3 [ 36 37 ] . Interestingly, srp1-31 also inhibits nuclear import of multiple proteins including Npl3 [ 51 52 ] . Remarkably, reduction-of-function alleles of the karyopherin KAP104 were also recovered in a screen for mutations that suppressed cdc15-2 ts (A.
The only phenotype known to be shared by srp1, mtr10, and kap104 mutants is accumulation of the 60S ribosomal protein Rpl11b in the nucleus [ 39 ] . SRP1, MTR10, and KAP104 may also collaborate to maintain the proper nucleocytoplasmic partitioning of α factor (or factors) that regulates mitotic exit.