Words similar to srf
Example sentences for: srf
How can you use “srf” in a sentence? Here are some example sentences to help you improve your vocabulary:
Therefore, when activated Ras is transfected with Elk-1, GAL4-SRF, and the reporter, the CAT activity increases to 8-fold over basal levels.
Interestingly, when all three constructs - SRF, Elk-1, and p35-C/EBPβ-are cotransfected with the reporter construct, there is an average 260-fold increase in CAT activity in the presence of activated Ras.
Based on the observations that TCF factors as well as p35-C/EBPβ: (1) interact with SRF (2) transactivate the SRE and (3) are responsive to Ras-dependent signaling pathways, we tested the possibility that both TCF and p35-C/EBPβ are necessary for maximal induction of the SRE in response to mitogenic stimulation.
This suggests that it is the transcriptional activation of a complex of SRF and its accessory proteins that is regulated rather than regulation of SRF DNA binding.
The SRF transactivation domain is weak, as has been shown previously [ 24].
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