Example sentences for: srf

How can you use “srf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • When CMV-Elk-1 is cotransfected with the reporter and GAL4-SRF, there is little increase in CAT activity in the absence of activated Ras (CMV-Ras.V12).

  • We constructed a GAL4 DNA binding domain-SRF fusion protein, as has been described previously [ 23].

  • In vivo footprinting analysis shows that SRF is constitutively bound to the SRE in both quiescent and growth factor stimulated cells [ 6].

  • The 5' flank of exon 1b was searched with TransFac for potential transcription factor binding sites [ 34 ] . Potential binding sites for three transcription factors that have been shown to play key roles in muscle gene expression were found, Sp-1, Mef2 and SRF [ 36 ] . Four potential Sp1 and two Mef2 bindings sites were found within 300 bps of the transcription start.

  • Due to the common observations that both Elk-1 and p35-C/EBPβ transactivate the SRE, interact with SRF, and are responsive to Ras-dependent signaling pathways, we hypothesized that Elk-1 and p35-C/EBPβ may both be necessary for maximal induction of SRF dependent transcription.


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