Example sentences for: srebp-

How can you use “srebp-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Hepatic SREBP-1 was down regulated with FISH and FUNG+FISH, but importantly, not affected with FUNG (-1.

  • [ 34 ] found AA to be more potent than DHA (saturated and monounsaturated being ineffective) at inhibiting activation of SREBP-1c promoter and LXRE enhancer constructs, induced by co-expression of LXRα or -β.

  • SREBP-1c, in addition to interacting with SREs, binds E-box containing promoters [ 38 ] . E-box containing promoters were not examined so the current data analysis could have underestimated SREBP-1-linked effects.

  • Chronic feeding of fish and AA-enriched fungal oils broadly affected genes regulated by PPARα, HNFα, and SREBP-1 in the liver; transcription factors implicated in lipid metabolism as well as other processes.

  • Numerous hepatic genes containing SRE promoters were regulated by LC-PUFA in the present experiments, including SREBP-1 itself (consistent with [ 35 36 ] ). Also regulated were genes involved in triacylglycerol synthesis (Gpam), FA synthesis and elongation (Acas1, Acly, FA synthase, Spot14, Elovl2; Elovl2 may speculatively contain an SRE as described by Moon and colleagues [ 35 ] ), FA desaturation (Scd1), gluconeogenesis (Pck1), cytochrome p450 metabolism (Cyp4a-10 and -14), FA transport (Cd36), cholesterol metabolism and transport (Fpps), and ketone body formation (mitochondrial Hmgcs2).


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