Words similar to sre
Example sentences for: sre
How can you use “sre” in a sentence? Here are some example sentences to help you improve your vocabulary:
We next tested the possibility that there could be a direct protein-protein interaction between Elk-1 and p35-C/EBPβ based on the fact that they synergize in transactivation of the SRE.
Based on the observations that TCF factors as well as p35-C/EBPβ: (1) interact with SRF (2) transactivate the SRE and (3) are responsive to Ras-dependent signaling pathways, we tested the possibility that both TCF and p35-C/EBPβ are necessary for maximal induction of the SRE in response to mitogenic stimulation.
However, when both Elk-1 and p35-C/EBPβ are transfected with the SRE reporter construct, there is a synergistic effect in transactivation of the SRE, with a 72-fold increase in CAT activity over reporter construct alone.
The SRE binds a transcription factor named serum response factor (SRF) which was found to be necessary, but not sufficient, for serum induction of the SRE [ 3, 4, 5].
Since Elk-1 and p35-C/EBPβ synergize in transactivation of SRF-dependent transcription using a GAL4-dependent promoter, we next tested if Elk-1 and p35-C/EBPβ could also synergize in transactivation of a native SRF binding site, namely the c-fos SRE.
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