Words similar to sre
Example sentences for: sre
How can you use “sre” in a sentence? Here are some example sentences to help you improve your vocabulary:
To this point, the TCF family members have been thought to be the main targets of Ras signaling to the SRE, and activation of TCF by Ras has been shown to result in transactivation of the SRE [ 16].
Upon activation of Ras-dependent signaling pathways, the presence of p35-C/EBPβ at the SRE would be stabilized due to its strong protein-protein interactions not only with SRF, as we have shown previously [ 23], but also with Elk-1.
In addition, it is likely that p35-C/EBPβ, Elk-1, or both, may need to be activated by one or more MAPK family members for a multiprotein complex to form with SRF at the SRE.
However, when both Elk-1 and p35-C/EBPβ are transfected with the SRE reporter construct, there is a synergistic effect in transactivation of the SRE, with a 72-fold increase in CAT activity over reporter construct alone.
Since Elk-1 and p35-C/EBPβ synergize in transactivation of SRF-dependent transcription using a GAL4-dependent promoter, we next tested if Elk-1 and p35-C/EBPβ could also synergize in transactivation of a native SRF binding site, namely the c-fos SRE.
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