Words similar to srebp
Example sentences for: srebp
How can you use “srebp” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although dietary LC-PUFA activated numerous transcriptional factors in both liver and hippocampus, it is a noteworthy difference that the transcriptional signatures for PPAR, SREBP, and HNF could not be detected in the hippocampal dataset.
It is not clear how AA is handled differently in the liver to prevent its interaction with SREBP.
For example, both upstream stimulating factor (USF; an E-box binding factor) and SREBP bind the FA synthase (Fasn) E-box [ 38 ] . Hepatic Usf2 transcription was significantly down regulated with FISH, but not affected by FUNG or the combination diet using microarrays, but this result could not fully be confirmed using RT-PCR (1.
Within the SREBP promoter element, the liver X receptor (LXR)-responsive elements (LXRE) may have an important role [ 34 ] . LC-PUFA may affect SREBP-1c mediated transcription via several mechanisms.
One mechanism is to antagonize activation of the LXR receptor leading to fewer LXR/RXR heterodimer complexes to bind the LXRE in the SREBP-1c promoter and less SREBP-1c-mediated transcription of SRE-containing genes [ 34 ] . The PPARα signaling cascade intertwines with SREBP pathways since LC-PUFA also activate PPARα, which can induce LXRα expression [ 17 ] .