Words similar to srebp

Example sentences for: srebp

How can you use “srebp” in a sentence? Here are some example sentences to help you improve your vocabulary:

Although dietary LC-PUFA activated numerous transcriptional factors in both liver and hippocampus, it is a noteworthy difference that the transcriptional signatures for PPAR, SREBP, and HNF could not be detected in the hippocampal dataset.
For example, both upstream stimulating factor (USF; an E-box binding factor) and SREBP bind the FA synthase (Fasn) E-box [ 38 ] . Hepatic Usf2 transcription was significantly down regulated with FISH, but not affected by FUNG or the combination diet using microarrays, but this result could not fully be confirmed using RT-PCR (1.
It is not clear how AA is handled differently in the liver to prevent its interaction with SREBP.
Within the SREBP promoter element, the liver X receptor (LXR)-responsive elements (LXRE) may have an important role [ 34 ] . LC-PUFA may affect SREBP-1c mediated transcription via several mechanisms.
One mechanism is to antagonize activation of the LXR receptor leading to fewer LXR/RXR heterodimer complexes to bind the LXRE in the SREBP-1c promoter and less SREBP-1c-mediated transcription of SRE-containing genes [ 34 ] . The PPARα signaling cascade intertwines with SREBP pathways since LC-PUFA also activate PPARα, which can induce LXRα expression [ 17 ] .