Words similar to srebp
Example sentences for: srebp
How can you use “srebp” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although dietary LC-PUFA activated numerous transcriptional factors in both liver and hippocampus, it is a noteworthy difference that the transcriptional signatures for PPAR, SREBP, and HNF could not be detected in the hippocampal dataset.
The elongase Elovl2 may contain an SRE, and therefore be under the transcriptional control of SREBP [ 35 ] ). Due to observations in the metabolite data, which suggests a repression of elongase activity, the dietary regulation of Elovl2 and Elovl3 was focused on.
It is not clear how AA is handled differently in the liver to prevent its interaction with SREBP.
Within the SREBP promoter element, the liver X receptor (LXR)-responsive elements (LXRE) may have an important role [ 34 ] . LC-PUFA may affect SREBP-1c mediated transcription via several mechanisms.
One mechanism is to antagonize activation of the LXR receptor leading to fewer LXR/RXR heterodimer complexes to bind the LXRE in the SREBP-1c promoter and less SREBP-1c-mediated transcription of SRE-containing genes [ 34 ] . The PPARα signaling cascade intertwines with SREBP pathways since LC-PUFA also activate PPARα, which can induce LXRα expression [ 17 ] .