Example sentences for: src

How can you use “src” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Recently, it has been found that the activation of Btk and Itk by Src family kinases is potentiated by and requires the activity of Phosphoinositide 3-kinase (PI3K), the products of which interact with the PH domains of Tec kinases [ 27, 28].

  • The v-crk SH2 domain interacts with YXXP motifs upon phosphorylation, suggesting that both of these regions may be able to interact with v-crk [ 37 ] . Fusions of the kinase inactive Src kinase domain and either the full Cas SD, the 5' region of the Cas SD (Cas(5'SD), containing 4 YQXP motifs) or the 3' of the Cas SD (Cas(3'SD), containing 9 YDXP motifs), are not stably tyrosine phosphorylated when expressed alone in cells (data not shown and see Fig.

  • In contrast, we have found that Rlk association with RAFTs, like its activation by Src family kinases, is PI3K independent.

  • Expression of the Src KMfused to the full length Cas SD, 5' N-terminal YQXP motifs or 3' C-terminal YDXP motifs alone demonstrated that these fusions were not stably tyrosine phosphorylated in cells (Fig.

  • It is also of note that we can reproducibly co-immunoprecipitate Rlk and Fyn, perhaps due to their association with RAFTs, whereas we have been unable to co-precipitate Itk with Src family kinases when co-expressed in 293T cells (data not shown), again demonstrating distinct properties of the Rlk protein compared to certain other members of the Btk family.


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