Words similar to src

Example sentences for: src

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The kinase domains of the c-Src Y416F mutant (kind gift of Dr. Joan Brugge, Harvard Medical School, Boston, MA) or the kinase inactive c-Src (K295M, [ 46 ] ), were amplified by PCR and cloned in pJ3H and pJ3M, two vectors for HA- and Myc-tagging at the N-terminus of the protein (kind gifts from Dr. J. Chernoff, Fox Chase Cancer Center, Philadelphia, PA, [ 47 ] ). The pEBG-JNK was a kind gift of Dr. Bruce Mayer (Harvard Medical School, Boston, MA).
These include SH3 domains (Src homology 3 domains, that bind to target proteins), MYTH4 (a domain of unknown function found in a few classes of myosins), a zinc-binding domain, a pleckstrin homology domain, FERM/talin (band 4.1/ezrin/radixin/moesin), GPA-rich domains and a protein kinase domain [ 8, 22, 26].
4b, lanes 1-3), although they can be stably tyrosine phosphorylated when fused to the attenuated Src kinase domain (data not shown and see Fig.
These results suggest that tyrosine 91 may be required for optimal phosphorylation and kinase activity of Rlk, but is distinct from the major site phosphorylated by Src family kinases.
Expression of the Src KMfused to the full length Cas SD, 5' N-terminal YQXP motifs or 3' C-terminal YDXP motifs alone demonstrated that these fusions were not stably tyrosine phosphorylated in cells (Fig.