Words similar to src
Example sentences for: src
How can you use “src” in a sentence? Here are some example sentences to help you improve your vocabulary:
This is not surprising since the ITAMs in CD79, which are proposed to be docking sites for Syk, are unlikely to be phosphorylated in the absence of BCR stimulation since phosphorylation of these residues likely requires activation of Src family tyrosine kinases expressed in B cells.
For a number of GPCRs, including the lysophosphatidic acid (LPAR) [ 7 ] , β-adrenergic 2 (β 2 -AR) [ 8 ] and μ- and δ-OR receptors [ 9 ] , the activation of a non-receptor tyrosine kinase of the Src or focal adhesion kinase (FAK) [ 10 ] families are involved.
To determine if the tyrosine phosphorylated chimera could compete with endogenous Cas for binding to endogenous c-crk, we transfected either the isolated attenuated Src kinase domain as control, or the tyrosine phosphorylated Cas substrate domain (Src*/Cas(SD)) into Cos-7 cells, and immunoprecipitated endogenous c-crk (Fig.
Although these distinctive features suggest that Rlk may have atypical functions, Rlk shares with Btk kinases the homologous proline-rich motif that binds the SH3 domains of Src kinases and the tyrosines at equivalent sites in the SH3 and kinase domains.
Some of the earliest changes that occur following BCR engagement are the activation of several non-receptor protein tyrosine kinases (PTKs), including p55 blk (Blk), p59 fyn (Fyn) and p53/56 lyn (Lyn) of the Src family [ 31 ] , Btk of the Itk/Tec family [ 32 33 ] and p72 Syk (Syk) of the Syk/ZAP-70 family [ 34 ] . The importance of Syk in BCR signaling and lymphocyte development has been clearly demonstrated using gene inactivation approaches.
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