Words similar to srl

Example sentences for: srl

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The exact SRL levels were not available as they were processed in central core laboratories, however were maintained at therapeutic level.
A number of studies have demonstrated that long treatment of both CsA and TAC is associated many side effects such as nephrotoxicity, hypertension, and gingival hyperplasia [ 1 2 ] . Rapamycin clinically termed, as Sirolimus (SRL) is a new immunosuppressive agent, which is structurally similar to TAC, binds to same binding protein FKBP, but has different mechanism of action [ 3 ] . Both clinical and experimental studies demonstrated that SRL when used either with CsA or alone is associated with side effects like hyperlipidemia, thrombocytopenia and nephrotoxicity [ 4 5 6 7 ] . SRL and TAC compete for the same binding site and hence it was thought they could not be used concomitantly.
The results from this study demonstrate that addition of SRL to TAC therapy results in a significant (p < 0.04) increase in circulating levels of TGF-β.
Azathioprine/MMF (Mycophenolate Motefil) were discontinued prior to initiation of SRL and all patients were on corticosteroids.
The results are shown in Figure 2which, demonstrated a significant inhibition of proliferation of lymphocytes from patients with TAC and SRL compared to TAC plus MMF/Aza.