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Example sentences for: sry

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This latter mechanism is thought to relate SRY to the X-linked SOX3 gene in mammals [ 23].
Note that the relevant transcriptional binding factor and/or co-activator for CRE (CREM and ACT) and for SRY in the adult (SRY) are testis-specific [ 37 38 ] . Future studies are necessary to determine if the transcriptional binding sites revealed by this study are functional in humans.
Long polyglutamine repeats have been found in a number of transcription factors [ 39 ] . Notably, the C-terminus of murine HMG-box protein SRY contains a large polyglutamine repeat region that is responsible for the sex-determining function of this protein [ 40 ] . However, a number of neurodegenerative disorders, such as Huntington disease and spinobulbar muscular atrophy, are also strongly associated with proteins containing a polyglutamine stretch [ 41 ] . Conformational change and protein misfolding in the expanded polyglutamine region is believed to be the molecular basis of the pathogenesis [ 42 ] . Whether the presence of polyglutamine repeats in the C-terminus of human TNRC9 is important for function or alternatively hinders its ability to form a functional protein remains to be determined.
Sry
Because there are rodent species with no SRY gene and no Y chromosome [ 16], any of these genes or the X-linked DAX1 gene [ 17] might be considered candidates for a sex-determining gene in the XX rodents such as mole voles whose body plan is not so different from that of mice.