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Example sentences for: sry
How can you use “sry” in a sentence? Here are some example sentences to help you improve your vocabulary:
Note that the relevant transcriptional binding factor and/or co-activator for CRE (CREM and ACT) and for SRY in the adult (SRY) are testis-specific [ 37 38 ] . Future studies are necessary to determine if the transcriptional binding sites revealed by this study are functional in humans.
Sry
Because there are rodent species with no SRY gene and no Y chromosome [ 16], any of these genes or the X-linked DAX1 gene [ 17] might be considered candidates for a sex-determining gene in the XX rodents such as mole voles whose body plan is not so different from that of mice.
These observations led to a search for the testis-determining factor on the Y chromosome culminating in isolation of the SRY gene [ 5], which is sex-determining in humans [ 6, 7] and mice [ 8].
Long polyglutamine repeats have been found in a number of transcription factors [ 39 ] . Notably, the C-terminus of murine HMG-box protein SRY contains a large polyglutamine repeat region that is responsible for the sex-determining function of this protein [ 40 ] . However, a number of neurodegenerative disorders, such as Huntington disease and spinobulbar muscular atrophy, are also strongly associated with proteins containing a polyglutamine stretch [ 41 ] . Conformational change and protein misfolding in the expanded polyglutamine region is believed to be the molecular basis of the pathogenesis [ 42 ] . Whether the presence of polyglutamine repeats in the C-terminus of human TNRC9 is important for function or alternatively hinders its ability to form a functional protein remains to be determined.
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