Words similar to prostaglandins
Example sentences for: prostaglandins
How can you use “prostaglandins” in a sentence? Here are some example sentences to help you improve your vocabulary:
These mediators, particularly tumor necrosis factor (TNF), interleukin (IL)-1, platelet activating factor, and prostaglandins, are thought to mediate the reduced peripheral vascular resistance seen in septic shock [ 4, 5, 6].
Many naturally occurring or synthetic compounds are agonists for the PPARs [ 20 21 ] . For example, a number of prostaglandins are agonists for PPARγ . The prostaglandin, 15-deoxy-delta 12, 14-PGJ 2 (15d-PGJ 2 ), is the most potent endogenous PPARγ agonist known.
It is well known that acute lung infection and septic shock may impair hypoxic pulmonary vasoconstriction through the massive release from activated endothelium of vasodilating mediators such as prostaglandins and endogenous NO, and hence result in disproportionately high shunting and hypoxemia [ 26, 27, 28, 29, 30, 31, 32].
Various studies have reported increased levels of prostaglandins and COX-2 expression in colorectal adenomas and adenocarcinomas obtained both from animals [ 40 41 ] and humans [ 42 43 44 ] . These findings have lead to the implication that COX-2 plays an important role in intestinal neoplasia and that the anti-neoplastic effects of NSAIDs are attributable to their ability to inhibit COX-2.
Cytosolic PLA 2 specifically hydrolyzes sn-2 arachidonate from phospholipid providing the precursors for many different lipid mediators including prostaglandins and leukotrienes [ 1 2 ] . These lipid metabolites play a role in acute inflammatory responses and also regulate normal physiological processes.
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