Words similar to prostaglandins

Example sentences for: prostaglandins

How can you use “prostaglandins” in a sentence? Here are some example sentences to help you improve your vocabulary:

Cytosolic PLA 2 specifically hydrolyzes sn-2 arachidonate from phospholipid providing the precursors for many different lipid mediators including prostaglandins and leukotrienes [ 1 2 ] . These lipid metabolites play a role in acute inflammatory responses and also regulate normal physiological processes.
Previous studies have demonstrated that acute endotoxemia activates peripheral blood neutrophils to release prostaglandins [ 17 ] . These lipid mediators are produced during inflammatory reactions largely via the enzyme COX-2 [ 18 ] . We found that COX-2 mRNA was markedly upregulated (40-400 fold) in adherent vascular lung neutrophils following endotoxin treatment of the animals (Fig.
Various studies have reported increased levels of prostaglandins and COX-2 expression in colorectal adenomas and adenocarcinomas obtained both from animals [ 40 41 ] and humans [ 42 43 44 ] . These findings have lead to the implication that COX-2 plays an important role in intestinal neoplasia and that the anti-neoplastic effects of NSAIDs are attributable to their ability to inhibit COX-2.
This most likely reflects the sustained role of prostaglandins during the inflammatory process [ 35 36 ] .
These mediators, particularly tumor necrosis factor (TNF), interleukin (IL)-1, platelet activating factor, and prostaglandins, are thought to mediate the reduced peripheral vascular resistance seen in septic shock [ 4, 5, 6].