Words similar to prostaglandins

Example sentences for: prostaglandins

How can you use “prostaglandins” in a sentence? Here are some example sentences to help you improve your vocabulary:

Many naturally occurring or synthetic compounds are agonists for the PPARs [ 20 21 ] . For example, a number of prostaglandins are agonists for PPARγ . The prostaglandin, 15-deoxy-delta 12, 14-PGJ 2 (15d-PGJ 2 ), is the most potent endogenous PPARγ agonist known.
Previous studies have demonstrated that acute endotoxemia activates peripheral blood neutrophils to release prostaglandins [ 17 ] . These lipid mediators are produced during inflammatory reactions largely via the enzyme COX-2 [ 18 ] . We found that COX-2 mRNA was markedly upregulated (40-400 fold) in adherent vascular lung neutrophils following endotoxin treatment of the animals (Fig.
These mediators, particularly tumor necrosis factor (TNF), interleukin (IL)-1, platelet activating factor, and prostaglandins, are thought to mediate the reduced peripheral vascular resistance seen in septic shock [ 4, 5, 6].
It is well known that acute lung infection and septic shock may impair hypoxic pulmonary vasoconstriction through the massive release from activated endothelium of vasodilating mediators such as prostaglandins and endogenous NO, and hence result in disproportionately high shunting and hypoxemia [ 26, 27, 28, 29, 30, 31, 32].
NSAIDs work, at least in part, by inhibiting cyclo-oxygenase, the enzyme that converts arachidonic acid to prostaglandins.