Example sentences for: prostaglandins

How can you use “prostaglandins” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • NSAIDs work, at least in part, by inhibiting cyclo-oxygenase, the enzyme that converts arachidonic acid to prostaglandins.

  • This most likely reflects the sustained role of prostaglandins during the inflammatory process [ 35 36 ] .

  • Cytosolic PLA 2 specifically hydrolyzes sn-2 arachidonate from phospholipid providing the precursors for many different lipid mediators including prostaglandins and leukotrienes [ 1 2 ] . These lipid metabolites play a role in acute inflammatory responses and also regulate normal physiological processes.

  • Certain prostaglandins are required for female reproduction and kidney function [ 3 4 5 ] . Because of its important role in controlling levels of arachidonic acid (AA), much attention has been focused on the regulation of cPLA 2 activation, with particular emphasis on the role of its phosphorylation and Ca 2+-mediated translocation [ 6 7 8 ] .

  • Many naturally occurring or synthetic compounds are agonists for the PPARs [ 20 21 ] . For example, a number of prostaglandins are agonists for PPARγ . The prostaglandin, 15-deoxy-delta 12, 14-PGJ 2 (15d-PGJ 2 ), is the most potent endogenous PPARγ agonist known.


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