Words similar to prostaglandin
Example sentences for: prostaglandin
How can you use “prostaglandin” in a sentence? Here are some example sentences to help you improve your vocabulary:
IDO regulates prostaglandin synthesis
[ 9 ] to be sufficient (significant) to reduce both polyp number and intestinal prostaglandin (PGE 2 ) content by greater than 45% when provided from 5-6 weeks of age to 16 weeks of age (i.e.
Here, he fills a syringe with the muscle-relaxant prostaglandin and swabs a spot near the base of his penis with rubbing alcohol.
3D = three-dimensional; MMP = matrix metalloproteinase; NE = neutrophil elastase; PGE 2 = prostaglandin E 2 .
COX-2 is an inducible enzyme upregulated in inflammatory states [ 20 21 ] . Notably, many NSCLC and what have been characterized as "premalignant" lung lesions have been shown to constitutively express the COX-2 enzyme and produce prostaglandin E-2 (PGE-2), the primary product of the COX-2 pathway [ 22 23 24 25 26 ] . Importantly, PGE-2 production by tumor cells has been linked to tumor-induced immunosuppression in NSCLC [ 2 3 4 5 ] . PGE-2 has been shown to directly suppress T cell mediated immunity, the primary effector against tumor cells, at a variety of levels [ 2 3 4 5 6 7 ] . Further, PGE-2 has been shown to induce the IL10 in mononuclear cells [ 4 5 ] . IL10 is a prominent immunosuppressive cytokine that may have a dominant role in preventing innate antitumor responses in the NSCLC environment [ 2 3 4 5 ] , [ 8 9 10 11 12 13 14 15 16 17 18 19 ] . Among myriad suppressive effects on T cells and antigen presenting cells, IL10 is known to inhibit IL12 production [ 14 15 16 17 18 ] . IL12 plays a key role in the initiation and potentiation of cellular immune responses and alteration of the IL12 producing function in circulating mononuclear phagocytes may be a critical factor in suppressed T cell immunity to NSCLC [ 27 28 ] .
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