Words similar to prostaglandin
Example sentences for: prostaglandin
How can you use “prostaglandin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Still, the prostaglandin is an inadequate fix for almost half of its users.
Multiparous western-range ewes were synchronized to estrus (= Day 0) with prostaglandin F 2 α (dinoprost tromethamine i.m.
The marginal efficacy of prostaglandin isn't likely to keep the baby boomers from buying the urological spin.
Prostaglandin E 2 is a major cyclooxygenase metabolite of arachidonic acid which exerts diverse effects on vascular smooth muscle tone and epithelial solute transport via G-protein coupled receptors [ 1 2 ] . At least four distinct G-protein coupled PGE 2 receptors have been cloned: the EP 1 , EP 2 , EP 3 , and EP 4 [ 1 ] . Pharmacological studies suggest PGE 2 relaxes vascular smooth muscle through two of these receptors, the EP 2 and EP 4 receptors, which couple to cyclic-AMP generation [ 3 ] . In contrast, PGE 2 constricts other vascular smooth muscle through EP 3 receptors which inhibit cAMP generation via G i or EP 1 receptors which increase Ca 2+mobilization [ 3 ] . Although both EP 2 and EP 4 receptors relax smooth muscle, EP 2 receptors are uniquely sensitive to the agonists butaprost and AH13205 [ 3 4 ] . Previous studies have shown that PGE 2 increases the cAMP concentration in many tissues including kidney, intestine and uterus, but the relative contribution of EP 2 versus EP 4 receptors to these effects is incompletely defined [ 5 6 ] . Recent studies in mice with targeted disruption of these receptors have suggested an important role for EP2 receptor in regulating systemic hemodynamics.
Supernatants were flash frozen in liquid nitrogen and stored at -80°C for subsequent determination of prostaglandin E 2 (PGE 2 ) content.
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