Words similar to prostate
Example sentences for: prostate
How can you use “prostate” in a sentence? Here are some example sentences to help you improve your vocabulary:
In a subsequent nested case-control study, stored serum samples from all cases of prostate cancer and a random sample of controls were tested for prostate-specific antigen (PSA).
Another possible mechanism by which a prostate cancer circumvents the low levels of androgens resulting from androgen ablation therapy is by increasing the sensitivity of AR to very low levels of androgens [ 42 ] . Stat3 increased the sensitivity of AR to a dose of androgen that showed no activity in the absence of Stat3, in the absence of a mutated AR.
CCI779 has been shown to have inhibitory effects on the growth of Pten -deficient tumors in the uterus and prostate in mice (KP & RP, submitted; M. Neshat & C. Sawyers, submitted).
This may reflect androgen activity in restoring the glandular structure by promoting postmitotic differentiation [ 48 49 ] . Consistent with this view, androgen administration to intact rats resulted in suppression of prostate epithelial cell proliferation and maintenance of morphological gland integrity [ 50 ] . Based on these findings, we propose that the effects of high doses of androgens on SKP2 and p27 in LNCaP cells described here reflect a differentiation and consolidation effect in vitro . If this is the case, LNCaP cells, despite being highly aneuploid derivatives of a metastatic lesion of an advanced cancer [ 39 ] , may have retained some aspects of the normal biphasic mechanism of androgen control observed in castrated rodents.
The current experiments investigate the effects of T and its interaction with RA on cell growth and the expression of RARs in human prostate cancer cells, LNCaP.
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