Example sentences for: probes

How can you use “probes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Some probes of library 614 showed strong red on the slide in Figure 1aand strong green on the slide in Figure 1bin the 614 section (Figure 1, arrowheads), which would be expected if these clones were expressed in a tissue-specific pattern.

  • Yeast ORFs were amplified from a set of 6,218 plasmids using universal primers as described [ 1 ] . This set of ORFs was printed on separate slides, hydrated, and snap-dried as described [ 1 ] . Mixed Cy5/Cy3-labeled probes were hybridized to microarrays for 12-15 h at 60°C.

  • Resuspended probes were mixed with 4 μl of 5 × hybridization buffer (20 × SSX, 1%SDS), 1 μl human Cot-1 DNA (10 μg/μl), 1 μl polyA DNA (2 μg/μl) (Amersham) and 8 μl formamide (Sigma, St. Louis, MO), heated to 65°C for 2 min and then centrifuged briefly.

  • 18 M NaCl/10 mM phosphate, pH 7.4/1 mM EDTA, 0.5% SDS) and rehybridized with probes made from mouse β-actin cDNA [ 54].

  • Oligodeoxyribonucleotide probes have been found to form duplexes with non-helical properties on positively charged surfaces [ 14 ] . These duplexes are highly asymmetrical and unwound, possibly incurring a significant loss in base stacking which may subsequently affect the energetics of duplex formation.


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