Words similar to probe-target
Example sentences for: probe-target
How can you use “probe-target” in a sentence? Here are some example sentences to help you improve your vocabulary:
At the molecular level, however, the microarray experiment is a challenging biophysical problem that is extremely dependent on probe-target kinetics, specificity and design.
It has been suggested [ 1] that a significant portion of the MM signal may derive from probe-target rather than background interactions; however, the relative contributions of specific and nonspecific components have not been established.
Recently, studies employing DNA arrays have also examined the use of modified nucleotides such as DAP, 5-bromodeoxyuridine, and 2'-O-methylthymidine in the probe [ 21 22 ] . An alternative method to increase the probe-target affinity is to incorporate the modified ribonucleotide, as the triphosphate derivative, during the IVT process so that the cRNA produced has the desired level of substitution of the corresponding unmodified nucleotide.
The addition of eukaryotic background had a profound effect on the properties of thermodynamic equilibrium of probe-target binding.
Each probe-target set contained a perfect DNA:RNA 30-mer match and 6 DNA:RNA pairs with 3-base mismatches incorporated into the oligodeoxyribonucleotide.