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Example sentences for: pkquest

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Other examples of PKQuest standard human parameters that were optimized this way are the muscle blood flow (optimized using human D 2 O pharmacokinetics [ 2 ] ) and the extracellular space (optimized using human inulin pharmacokinetics [ 3 ] ).
The philosophy behind the use and development of PKQuest differs from that of the standard PBPK applications.
By using all the previous information that is available to restrict the model and minimize the number of adjustable parameters, PKQuest greatly increases the predictive power of the analysis.
However, PKQuest does incorporate a number of features that are not present in Mapleson's model, including tissue metabolism, capillary limitation (either in the lung or tissue) and ventilation-perfusion mismatch.
The agreement between the PKQuest predictions and experiment is excellent for the N 2 O uptake.