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Example sentences for: peroxisomes
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The third control was the presence of a contaminant organelle, peroxisomes (Fig.
Alternatively, peroxisomes might be involved in membrane breakdown in the mitochondrial degeneration process.
Peroxisomes shorten chains of very long fatty acids, unsaturated fatty acids and branched fatty acids by β-oxidation [ 60 61 ] . They play critical roles in synthesis of ether phospholipids and cholesterol [ 62 63 ] . Peroxisomal abundance is associated with high membrane demand such as myelination in the central nervous system [ 64 65 ] and peroxisome diseases result in defective myelination [ 66 ] . Because the outer mitochondrial membrane normally tightly wraps around mitochondria, the extension of the outer membrane during vacuolation requires new membranes.
These results suggest that peroxisomes actively participate in the formation of mitochondrial vacuoles at the early stages.
Because, in addition to mitochondria, peroxisomes are also involved in phospholipid synthesis and metabolism (see Discussion), we examined whether peroxisomes might participate in vacuole formation.