Example sentences for: peroxynitrite

How can you use “peroxynitrite” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In AGS cells, ascorbic acid caused a reduction in the apoptotic response to peroxynitrite (P < 0.01).

  • This result is not specific to a particular oxidant, as a comparable response was observed with the three distinct oxidants - peroxynitrite, hydrogen peroxide, and the free radical DPPH.

  • Additionally, it appears that the population sub-groups at greatest risk for gastric cancer have a limited ability to secrete ascorbic acid from the plasma through the mucosal and into the gastric lumen [ 30 ] . In a related study, supplementation with vitamin C reduces the degree of apoptosis and nitrotyrosine immunohistochemistry [ 13 ] , a marker of peroxynitrite formation [ 15 ] . NF-κB is activated in gastric epithelia with H. pylori infection, and clearance of this infection reduced NF-κB levels as well as expression of inducible nitric oxide [ 5 13 ] , thereby reducing the mucosal burden of nitric oxide and possibly peroxynitrite.

  • However, endogenous production of peroxynitrite remains controversial.

  • Quenching of peroxynitrite was not evaluated as it can only be effectively studied at a severe alkaline pH, given the lability of peroxynitrite at neutral pH.


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