Words similar to peroxynitrite
Example sentences for: peroxynitrite
How can you use “peroxynitrite” in a sentence? Here are some example sentences to help you improve your vocabulary:
We have also demonstrated that mesalamine (5-aminosalicylic acid), used as a frontline treatment for inflammatory bowel disease, could prevent apoptotic epithelial cell death in response to peroxynitrite [ 14 ] . Peroxynitrite is a potent oxidant; formed from two free radicals - nitric oxide and superoxide - that catalyzes the nitration of tyrosine residues.
Cell death in response to Peroxynitrite
Peroxynitrite is a potent oxidant that can induce lipid peroxidation and as such may provide important insight.
Cells were treated with DPPH (3 μM), H 2 O 2 (50 μM), peroxynitrite (300 μM) and/or supplemented with 10 μg/ml of each antioxidant (cat's claw, green tea, ascorbic acid), and incubated for 6 h.
The first proposes that the mutated SOD1 interacts with NO to produce peroxynitrite (ONOO -), which damages proteins by modifying tyrosine to nitrotyrosine residues [ 42 43 44 ] . The second postulates that the mutant SOD1 possesses an enhanced peroxidase activity, which causes oxidative modification of nucleic acids, proteins and lipids [ 45 46 47 ] . Both of these activities require copper at the active center of SOD1.