Example sentences for: overexpression

How can you use “overexpression” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Testing specific genes by overexpression in transgenic flies is a candidate gene approach, meaning that the investigator must make an educated guess as to which genes are worth assaying by this relatively labor-intensive method.

  • It is possible that in some of the lines the increase in life span between -DOX and +DOX is reduced because there is already some gene overexpression and life-span extension in the -DOX flies.

  • In contrast, cyclin E levels, while not initially affected by MIB, were decreased after 72 h of SKP2 overexpression (Fig.

  • Additionally, since the identification and cloning of the p27 gene in 1994 [ 16 ] , the p27 protein has been shown to be involved in various other aspects of cell physiology and pathology [ 17 ] . Our previous study has shown, that differentiation of cells in tissue culture is associated with an increase in p27 expression [ 18 ] . Although a regular p27 expression protects normal cells from apoptosis, overexpression of p27 induces apoptosis of cells, through elevation of proapoptotic proteins, such as Bax [ 19 20 ] . These observations indicate that changes in p27 expression can determine the fate of muscle cells.

  • After confirmation of the sequence, the mutated pL1PUC19 plasmid was digested with Nde I and Hind III, and the 900 bp, mutated L1 gene was gel purified and ligated into pET26b to create the mutant overexpression plasmids.


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