Example sentences for: overexpression

How can you use “overexpression” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Finally, the effect of CaM overexpression on Siah1a function was assessed.

  • Effect of overexpression of Bcl-3 on the inhibition of MMP-1 by CDDO

  • Overexpression of eIF4E leads to deregulated growth and malignant transformation of a variety of cultured cell lines [ 12 13 14 ] . Moreover, elevated levels of eIF4E are commonly found in solid tumors, especially in breast, colon, and head and neck tumors [ 15 ] . Clinical studies indicate that eIF4E gene amplification and protein overexpression is associated with malignant progression in these tumors [ 16 ] . High eIF4E levels are also associated with a higher rate of cancer recurrence and cancer-related death [ 17 ] . In contrast to eIF4E, overexpression of 4EBP inhibits cell proliferation [ 18 ] and 4EBP-1 expression levels are inversely correlated with the progression of certain types of tumors [ 19 ] .

  • This is in contrast to overexpression of SOD genes or certain single gene mutations such as mth , where life-span increases range from 20 to 50% [ 14, 23, 24, 25].

  • Overexpression of the antioxidant enzyme peptide methionine sulfoxide reductase is also associated with increased life span [ 26].

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