Example sentences for: overexpressed

How can you use “overexpressed” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Conversely, the expression of thrombospondin-1 (TSP-1) [ 4 ] and of tyrosinase-related protein-1 (TYRP-1) was markedly overexpressed in the nonmetastatic NM-2C5 cell line [ 2 5 ] .

  • To begin to identify genes that might be targets of BP1, we have overexpressed BP1 in K562 cells and screened a microarray (Davenport GJ, Fu S, Haga SB, Do K, Stevenson H, Pinzone J, Chase MB, Berg PE, unpublished data).

  • It was suggested that this excess neural tissue arose from specification of excess uncommitted precursor cells to a neural fate once levels of the overexpressed Notch protein fell.

  • Seven percent is certainly a large underestimate of the frequency at which genes are overexpressed, as embryogenesis was not tested, and not all genes will be lethal or have an obvious visible phenotype when overexpressed.

  • In later stages of tumorigenesis, TGFβ can act as a stimulator of invasion and metastasis [ 3 ] acting directly on the tumor cells or inducing angiogenesis and facilitating local and systemic immunosuppression, respectively [ 4 ] . For example, TGFβ may stimulate the expression of proteases such as uPA, MMP-3 or MMP-9, enzymes frequently overexpressed in invasive tumor cells [ 5 6 ] .


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