Words similar to overexpressing
Example sentences for: overexpressing
How can you use “overexpressing” in a sentence? Here are some example sentences to help you improve your vocabulary:
[ 22 ] developed transgenic (TG) mice overexpressing rat ABP.
, 1998), it has been proposed that there is a need for caution in interpreting p53 function on the basis of cells transiently overexpressing this protein.
Mice overexpressing collagenase, however, develop emphysema [ 14].
It is well established that TG mice overexpressing rat ABP [ 22 ] develop a testicular impairment [ 23 24 25 ] leading gradually to a reduced number of germ cells and infertility [ 26 ] . Various theories were proposed to explain the possible mechanisms behind this testicular impairment seen in the ABP-TG mice overexpressing rat ABP.
It has been demonstrated that malignant tissues with accelerated cell cycle show higher levels of ProTα expression than normal or surrounding healthy tissues [ 67 ] . ProTα was shown as a marker for breast cancer [ 68 ] , hepatocarcinoma [ 69 ] , and plasma levels of its derivative Tα 1 been proposed as a marker for the prognosis of lung cancer [ 70 ] . In ligand blotting assays, ProTα bound only to chromatin pools and nuclear fractions where histone H1 was present [ 71 72 ] . The analysis of the interaction of ProTα with H1-containing chromatin suggests a putative role for ProTα in the fine-tuning of the stoichiometry and/or mode of interaction of H1 with chromatin [ 73 ] . Interestingly, HL-60 cells overexpressing ProTα show an enhancement of accessibility of micrococcal nuclease to chromatin, implying relaxed chromatin structure for enhanced cell cycle gene expression [ 74 ] .
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