Words similar to nm-
Example sentences for: nm-
How can you use “nm-” in a sentence? Here are some example sentences to help you improve your vocabulary:
While clone M-4A4 aggressively metastasizes to the lung and lymph nodes, the NM-2C5 clone is entirely nonmetastatic.
In an effort to establish a methodological framework for analysis of the molecules and the mechanisms involved in this complex multistep process, we previously developed a well-defined experimental system in which the role of candidate genes can be screened and tested [ 2 ] . By serial dilution cloning of the MDA-MB-435 tumor cell line and screening by orthotopic implantation into the mammary fat pad of athymic mice, we derived a pair of breast tumor cell lines (M-4A4 and NM-2C5) that originate from the same breast tumor, but that have diametrically opposite metastatic capabilities.
Primary tumors recovered from nude mice inoculated with the M-4A4 and NM-2C5 MDA-MB-435 clones [ 2 ] were used as positive controls.
Our finding that TYRP-1 is also expressed in the poorly metastatic or noninvasive cell lines NM-2C5 [ 2 ] , T47D, MCF7 and DU145 [ 5 ] , which are derived from human breast cancers and prostate tumors that are nonmetastatic, indicates that this molecule is not exclusively expressed in cells of the melanocytic lineage.
Conversely, the expression of thrombospondin-1 (TSP-1) [ 4 ] and of tyrosinase-related protein-1 (TYRP-1) was markedly overexpressed in the nonmetastatic NM-2C5 cell line [ 2 5 ] .