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Example sentences for: nm-

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Conversely, the expression of thrombospondin-1 (TSP-1) [ 4 ] and of tyrosinase-related protein-1 (TYRP-1) was markedly overexpressed in the nonmetastatic NM-2C5 cell line [ 2 5 ] .
In an effort to establish a methodological framework for analysis of the molecules and the mechanisms involved in this complex multistep process, we previously developed a well-defined experimental system in which the role of candidate genes can be screened and tested [ 2 ] . By serial dilution cloning of the MDA-MB-435 tumor cell line and screening by orthotopic implantation into the mammary fat pad of athymic mice, we derived a pair of breast tumor cell lines (M-4A4 and NM-2C5) that originate from the same breast tumor, but that have diametrically opposite metastatic capabilities.
In lamina I, large vesicles (120 nm-150 nm) were labelled in the cytoplasm close to the plasma membrane (Fig.
While clone M-4A4 aggressively metastasizes to the lung and lymph nodes, the NM-2C5 clone is entirely nonmetastatic.
Primary tumors recovered from nude mice inoculated with the M-4A4 and NM-2C5 MDA-MB-435 clones [ 2 ] were used as positive controls.