Words similar to niii

Example sentences for: niii

How can you use “niii” in a sentence? Here are some example sentences to help you improve your vocabulary:

Thus far, this phenotype segregates as an autosomal recessive trait and maps to the FEOM2 locus on chromosome 11q13 [ 8 ] , and affected individuals carry homozygous mutations in ARIX [ 5 ] . ARIX encodes a homeodomain transcription factor required for nIII and nIV development in mice and zebrafish [ 22 23 ] . In families with CFEOM3, the CFEOM phenotype is variably expressed.
This finding is consistent with our prediction that, compared to ARIX, the genes mutated in CFEOM1 may have a more restricted function in the development of nIII and that their expression may actually be regulated by ARIX.
Although several distinct CFEOM phenotypes have been defined [ 6 7 8 ] , each likely resulting from maldevelopment of a unique combination of alpha motor neurons in nIII and/or nIV, most reports of CFEOM families describe a stereotypical clinical phenotype.
These phenotypes are classified as CFEOM based on the presence of affected members with congenital restrictive ophthalmoplegia affecting extraocular muscles in the nIII/nIV distribution.
ARIX, which encodes a transcription factor critical to nIII and nIV development in mice and zebrafish [ 22 23 ] , was recently identified as the FEOM2 gene mutated in affected members of CFEOM2 families [ 5 ] . It was unknown, however, if classic CFEOM may also result from mutations in this gene.