Words similar to nls
Example sentences for: nls
How can you use “nls” in a sentence? Here are some example sentences to help you improve your vocabulary:
To verify if the spots in nuclei correspond to the tagged loci, we examined whether the detected subnuclear localization of the expressed GFP-LacI/NLS fusion protein is sensitive to isopropyl-β-D-thiogalactoside (IPTG).
The copy numbers of insertions in these lines were estimated with restriction digests of genomic DNA using Bgl II and Hind III in addition to Pst I, followed by Southern blot analysis using the LacI/NLS fragment as a probe (Figures 1, 2).
This sequence is the likely nuclear localization signal (NLS) for these proteins [ 15 ] , similar to the bipartite NLS found in nucleoplasmin [ 36 ] . The one exception is the Langerhans cell protein-1 (LCP1)/KIAA0737 pair, which lacks the second basic residue of the motif.
A gene encoding a plant-optimized GFP variant, mGFP5 [ 24], was placed in frame with a LacI -SV40 nuclear localization signal fusion ( GFP-LacI/NLS ) [ 25] and then subcloned into the vector pTA7002 under the control of the glucocorticoid receptor (GR)-responsive promoter near the left border.
Since the RING finger is a protein-protein interaction domain, interaction of the mammalian COP1 RING finger with another protein may, under certain conditions, trigger a conformational change of the surrounding peptides, altering the proximity between the two positive residue clusters of the NLS to disrupt binding to the nuclear import machinery.
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