Example sentences for: nls

How can you use “nls” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A putative NLS is also present in the N-terminus of Pop1p located between the F-box and the WD-repeat domain ( 393PEKIKRC).

  • LacI/NLS sequence in the inserts as well as restriction sites present at variable distances in the genomic DNA neighboring the left border of the insertions.

  • Finally, it should be noted that a recent study using cell lines raised the possibility that SN50's action is not specific to NF-κB [ 61 62 ] . SN50 is composed of the NLS for NF-κB p50 and was believed to specifically block NF-κB p50/p65 nuclear translocation by binding the NLS receptor complex and preventing transport through the nuclear pore [ 33 34 35 ] . However, Torgerson and coworkers [ 61 ] have shown that SN50 treatment inhibited nuclear transport of transcription factors NFAT, AP-1, STAT1, and NF-κB at a high dose of 210 μg/ml in Junkrat cells.

  • This sequence is the likely nuclear localization signal (NLS) for these proteins [ 15 ] , similar to the bipartite NLS found in nucleoplasmin [ 36 ] . The one exception is the Langerhans cell protein-1 (LCP1)/KIAA0737 pair, which lacks the second basic residue of the motif.

  • Outside of the HMG-box and NLS, the murine and human homologues of the three additional pairs of proteins are highly conserved, as we reported for TOX and KIAA0808 [ 15 ] . LCP1 and KIAA0737 proteins are approximately 94% identical, while LOC241768 and C20ORF100 share 85% identity.


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