Words similar to nf-y
Example sentences for: nf-y
How can you use “nf-y” in a sentence? Here are some example sentences to help you improve your vocabulary:
In this study, we examine the characteristics of DEK binding to the Y-box sequences of DQA1*0101, DQA1*0501, DRA, DQB , and DRB . We also confirm participation of DEK with NF-Y in the DQA1 Y-box binding complex and localize specific DEK binding within this sequence.
NF-Y binding to the MHC class II gene Y box anchors a complex assembly of nuclear proteins that occupies several regulatory elements over a great distance [ 20 21 22 ] . In the DQA1 promoter Y box, a reverse CCAAT motif with a partially overlapping TG-rich sequence shares sequence identity with the HIV-2 DEK-binding site at 7 of 10 positions (Fig.
Divergence of the HLA-DQA1*0501 Y-box sequence at one position within the required NF-Y binding site reduces its ability to compete with the DRA Y-box probe (Fig.
Consistent protection is also seen at position 2, adjacent to the A-for-G substitution that diverges from the Y-box consensus sequence, although there is no protection of the divergent base itself at position 3. DNase I protection by recombinant DEK extends over the length of the Y-box sequence, including bases within the NF-Y binding site (reverse CCAAT sequence), again suggesting that the two proteins may interact.
The NF-Y transcription factor adds further complexity to transcriptional regulation since it can interact and modulate the expression of SREBP-1c target genes containing Y-box motifs, such as those found in Fasn [ 37 ] . Mutating the NF-Y binding site in Fasn relieved LC-PUFA-induced Fasn down regulation [ 39 ] . Nfyb was differentially expressed after dietary LC-PUFA addition (1.
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