Words similar to nf-kb

Example sentences for: nf-kb

How can you use “nf-kb” in a sentence? Here are some example sentences to help you improve your vocabulary:

For example, PPARγ is involved in a positive feedback mechanism that induces the formation of foam cells [ 23 ] . On the other hand, activation of PPARγ was shown to inhibit monocyte [ 24 ] and macrophage [ 25 ] inflammatory responses by preventing the activation of nuclear transcription factors, such as NF-kB (nuclear factor-kappa B), AP-1 (activator protein-1) and STAT 1 (signal transducer and activator of transcription 1).
Figure 2Cshows that TNF-α (20 ng/ml) significantly increased nuclear translocation of p65, a subunit of the p50/p65 NF-kB complex.
SP1 and possibly AP2, Adh1 (ETF), PEA3 sites [ 32] which could also contribute to NF-kB dependent gene activation and might participate in NO mediated MAdCAM-1 regulation by cytokines.
Therefore, NO might limit NF-kB activation through pathways independent of IkB-a.
TNF-α is a well-characterized, potent inducer of IL-8 transcription and an anti-apoptotic agent [ 30 31 32 ] . Roebuck provides a detailed analysis of IL-8 promoter structure including a promoter recruitment mechanism which involves TNF-α and the cooperativity of NF-kB and NF-IL-6 binding sites [ 4 32 ] . TNF-α exerts many of its effects through TNFR-1 and TNFR-2 receptors, thus co-expression of these receptors with IL-8 might be anticipated.