Words similar to nf-kb
Example sentences for: nf-kb
How can you use “nf-kb” in a sentence? Here are some example sentences to help you improve your vocabulary:
In that report, NO was found to induce IκB synthesis through activation of its promoter, therefore, increased IkB-a might also contribute to NF-kB inhibition . Several other possible pathways, e.g. p38, p42/44 MAPK and transcription factors, e.g.
For example, PPARγ is involved in a positive feedback mechanism that induces the formation of foam cells [ 23 ] . On the other hand, activation of PPARγ was shown to inhibit monocyte [ 24 ] and macrophage [ 25 ] inflammatory responses by preventing the activation of nuclear transcription factors, such as NF-kB (nuclear factor-kappa B), AP-1 (activator protein-1) and STAT 1 (signal transducer and activator of transcription 1).
Similarly, GSNO also reduced NF-kB activation (as measured by EMSA).
We have described in vitro that exogenous IL-10 can block the expression of MAdCAM-1 in response to TNF-α, and attenuates lymphocyte adhesion to lymphatic node derived endothelium under cytokine stimulating conditions via NF-kB inhibition [ 5 ] . The purpose of the current study was to show that induction of endothelial expression of IL-10 through an IL-10 expression vector attenuates MAdCAM-1 expression in response to TNF-α and optimistically suggests the possibility of targeted Th2-cytokine gene therapy in IBD.
MAdCAM-1 (mucosal addressin cell adhesion molecule-1), IL-10 (Interleukin-10), HEV (high endothelial venular), ECAMs (endothelial cell adhesion molecules), IBD (inflammatory bowel diseases), UC (ulcerative colitis), CD (Crohn's disease), ICAM-1 (intracellular adhesion molecule 1), VCAM-1 (vascular adhesion molecule 1), NF-kB (nuclear transfection factor kB), TNF-α (tumor necrosis factor alpha), GM-CSF (granulocyte-macrophage colony-stimulating factor), GCSF (granulocute colony stimulating factor), ECL (enhanced chemiluminescence)
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