Words similar to nf-h

Example sentences for: nf-h

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Amino acid sequences predicted by PhosphoBase as serine, threonine, or tyrosine phosphorylation motifs for NF-H were then compared to the aligned proteins in regions of high identity, as determined by reliability scores generated by the Match-Box server [ 25 ] .
In SH-SY5Y cell extracts, the SMI-31 and SMI-32 lanes show strong labeling of bands corresponding to the MW of NF-H and NF-M.
Thus, it appears that SMI-31 recognizes a phosphoepitope that occurs on proteins in addition to NF-H and NF-M, as previously reported (see the Discussion for other reports of SMI-31 staining glial cells in situ ). RT-97 also labeled nuclear and cytoplasmic structures in F98 cells (Figure 1E).
The calculated molecular weights of lamins A, B and C are approximately 74, 66, and 65 kDa, respectively; therefore, it seems most likely that lamins, NF-H, and GFAP all share a common motif that, when phosphorylated, is recognized by SMI-31 and RT-97 mABs.
In support of this, a search for phosphorylation motifs among NF-H, GFAP and lamins A, B, and C revealed a single, high probability tyrosine site that occurs once on each of these proteins (Figure 3), further suggesting the possibility that this site constitutes or is contained within the epitope recognized by these two antibodies.