Words similar to nf-at
Example sentences for: nf-at
How can you use “nf-at” in a sentence? Here are some example sentences to help you improve your vocabulary:
A recent report demonstrated that Wnt-5a and Rfz-2 can induce the nuclear localization of the transcription factor NF-AT [ 14 ] . Their results show that NF-AT is a downstream target of the Wnt/Ca 2+pathway and antagonizes the Wnt/beta-catenin pathway in Xenopus embryos.
In addition, this CD5 response to BCR stimulation has been shown to be mediated in part by vav-2, which activates of NF-AT [ 49].
This enhancer element, located at approximately 2 kb upstream of the translation start on the CD5 promoter, is dependent on NF-AT activation to induce CD5 expression in anti-IgM stimulated primary splenic cells cultured with LPS for 3 days [ 48].
The SL-1 promoter has putative NF-AT binding sites but whether these are important for Wnt-5a regulation requires further testing.